Results 61 to 70 of about 11,639,456 (287)

Influenza virus detection: driving change in public health laboratories in the Western Pacific Region

Western Pacific Surveillance and Response, 2019
As we observe the 100th anniversary of the 1918 influenza pandemic, we are reminded of the importance of preparedness for and adequate response to influenza, and the critical role of influenza surveillance through laboratory detection.
Raynal C Squires, Patrick C Reading, Sheena G Sullivan, Ian G Barr, Frank Konings   +4 more
doaj   +1 more source

The Wisconsin Plasma Astrophysics Laboratory

, 2015
The Wisconsin Plasma Astrophysics Laboratory (WiPAL) is a flexible user facility designed to study a range of astrophysically relevant plasma processes as well as novel geometries that mimic astrophysical systems. A multi-cusp magnetic bucket constructed
Brookhart, M., Clark, M., Cooper, C. M., Desangles, V., Egedal, J., Endrizzi, D., Flanagan, K., Forest, C. B., Khalzov, I. V., Li, H., Miesch, M., Milhone, J., Nornberg, M., Olson, J., Peterson, E., Roesler, F., Schekochihin, A., Schmitz, O., Siller, R., Spitkovsky, A., Stemo, A., Wallace, J., Weisberg, D., Zweibel, E.   +23 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

The Psychological Effects of Terrorism are Moderated by Cultural Worldviews [Les Effets Psychologiques du Terrorisme sont Modérés par les Normes Culturelles]

International Review of Social Psychology, 2016
Terrorism cannot be easily studied experimentally for obvious reasons. We report the results of a laboratory study ('N' = 149) testing the effect of cultural worldviews on feelings of threat and hostility toward Muslims in France that include in the ...
Armelle Nugier, Elodie Roebroeck, Nolwenn Anier, Emmanuelle P. Kleinlogel, Armand Chatard, Serge Guimond   +5 more
doaj   +1 more source

Regular laboratory testing and patient survival among patients undergoing maintenance hemodialysis: a Korean nationwide cohort study [PDF]

, 2023
Do Hyoung Kim, Ajin Cho, Hayne Cho Park, Bo‐Yeon Kim, Miri Lee, Gui Ok Kim, Jin‐Seog Kim, Young‐Ki Lee   +7 more
openalex   +1 more source

Iyer Laboratory Solid Tissue Chromatin Immunoprecipitation Protocol [PDF]

, 2017
A detailed protocol on how to perform chromatin immunoprecipitation in solid tissue samples.
Hall, Amelia
core   +1 more source