Results 141 to 150 of about 1,536,423 (242)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Biodistribution of Mesenchymal Stromal Cells Labeled with [89Zr]Zr-Oxine in Local Radiation Injuries in Laboratory Animals. [PDF]

open access: yesMolecules, 2023
Astrelina TA   +14 more
europepmc   +1 more source

POTENTIAL INFLUENCE OF IMMUNOMODULATORS ON THE PRODUCTION OF INTERFERON-GAMMA AND INTERLEUKIN-10 IN LABORATORY ANIMALS VACCINATED AGAINST PLAGUE

open access: diamond, 2018
A. Yu. Goncharova   +5 more
openalex   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

A Workflow for Assessing Particle Counts of Mixed Micro- and Nanoplastics in Exposed Laboratory Animals. [PDF]

open access: yesNanomaterials (Basel)
Gaspar L   +5 more
europepmc   +1 more source

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