Results 181 to 190 of about 2,504,342 (301)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Nav1.8 and Chronic Pain: From Laboratory Animals to Clinical Patients. [PDF]

Biomolecules
Xie YF.
europepmc   +1 more source

Biodistribution of Fluorescent Albumin Nanoparticles among Organs of Laboratory Animals after Intranasal and Peroral Administration. [PDF]

Curr Issues Mol Biol, 2023
Morozova O, Isaeva E, Klinov D.
europepmc   +1 more source

Pain and laboratory animals [PDF]

Nature, 1985
openaire   +5 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Federal Regulation of Testing with Laboratory Animals: Future Directions [PDF]

, 1986
Reagan, Kinsey S.
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Workflow for Assessing Particle Counts of Mixed Micro- and Nanoplastics in Exposed Laboratory Animals. [PDF]

Nanomaterials (Basel)
Gaspar L, Davis S, Coppotelli G, Davies AJ, Suckling CC, Ross JM.   +5 more
europepmc   +1 more source

Biodistribution of Mesenchymal Stromal Cells Labeled with [⁸⁹Zr]Zr-Oxine in Local Radiation Injuries in Laboratory Animals. [PDF]

Molecules, 2023
Astrelina TA, Brunchukov VA, Kodina GE, Bubenshchikov VB, Larenkov AA, Lunev AS, Petrosova KA, Rastorgueva AA, Kobzeva IV, Usupzhanova DY, Nikitina VA, Malsagova KA, Kulikova LI, Samoilov AS, Pustovoyt VI.   +14 more
europepmc   +1 more source

Laboratory Animals [PDF]

Nature, 1967
openaire   +1 more source