Results 61 to 70 of about 1,631,615 (310)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Historical development path of the Laboratory of biochemistry of adaptation and ontogenesis of animals

open access: yes, 2020
The article presents a historical development path of the Laboratory of biochemistry of adaptation and ontogenesis of animals which began with the founding of the Ukrainian Research Institute of Physiology and Biochemistry of Farm Animals in 1960. At the
H. V. Klymets   +2 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rapid detection of three rabbit pathogens by use of the Luminex x-TAG assay

open access: yesBMC Veterinary Research, 2018
Background Domestic rabbits especially New Zealand white rabbits play an important role in biological research. The disease surveillance and quality control are essential to guarantee the results of animal experiments performed on rabbits.
Miaoli Wu   +10 more
doaj   +1 more source

Role of the International Council for Laboratory Animal Science (ICLAS) in the promotion of care and use of laboratory animals in Southeast Europe [PDF]

open access: yesArchives of Biological Sciences, 2008
The use of animals in research, teaching, and testing is regulated around the world by specific laws. Since regulatory processes are highly variable, a broad variability in the care and use of animals in scientific procedures exists internationally, as ...
Kostomitsopoulos N.   +2 more
doaj   +1 more source

Report of the Federation of European Laboratory Animal Science Associations Working Group on animal identification

open access: yes, 2013
The primary aim of this report is to assist scientists in selecting more reliable/suitable identification (ID) methods for their studies. This is especially true for genetically altered (GA) animals where individual identification is strictly necessary ...
Sveriges lantbruksuniversitet.   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Statistical design for health monitoring in laboratory animal facilities using sentinel animals

open access: yes
Regular health monitoring is crucial in laboratory animal facilities to determine the presence or absence of specific pathogens. One common approach to monitoring involves the use of sentinel animals, which are periodically exposed to biological material
Sorzano, Carlos Oscar S   +2 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Anesthesia and analgesia in laboratory animals /

open access: yes, 1997
Anesthesia and Analgesia in Laboratory Animals focuses entirely on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery.
Kohn, Dennis F.
core  

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