Results 81 to 90 of about 2,504,342 (301)
Effects of inhalation of Freon 113 on laboratory animals [PDF]
Four monkeys, 8 dogs, 40 mice, and 50 rats were exposed continuously to 2000 ppm Freon 113 in a Thomas Dome for 14 days. This exposure produced no mortalities nor adverse symptomology.
Back, K. C. +3 more
core +1 more source
Animal emergence during Snowball Earths by thermosynthesis in submarine hydrothermal vents [PDF]
, 2009 Darwin already commented on the lateness in the fossil record of the emergence of the animals, calling it a valid argument against his theory of evolution^1^.
Anthonie W. J. Muller
core +2 more sources
Categories, concepts, and calls : auditory perceptual mechanisms and cognitive abilities across different types of birds. [PDF]
, 2013 Although involving different animals, preparations, and objectives, our laboratories (Sturdy's and Cook's) are mutually interested in category perception and concept formation.
Cook, Robert +4 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 The Mugilogobius myxodermus is an endemic freshwater fish in china. Herein, we sequenced and assembled the first complete mitogenome of M. myxodermus. The total length of the mitogenome is 16,495 bp, containing 13 protein-coding genes, two ribosomal RNAs
Lei Cai, Ren Huang, Jianjun Li
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Amphibians as Laboratory Animals [PDF]
ILAR Journal, 1995 Scientists Center for Animal Welfare (Available from SCAW, Golden Triangle Building One, 7833 Walker Drive, Suite 340, Greenbelt, MD 20770. Tel: 301/345-3500; Fax: 301/345-3503). Scott WB, Crossman EJ. 1973. Freshwater Fish of Canada. Fisheries Research Board of Canada, Bulletin 184. Snodgrass MJ, Burke JD, Meetz GD. 1976.
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Клінічна та профілактична медицина, 2019 The aim of the study. To investigate in experimental conditions the effect of bismuth citrate on the immune system of laboratory animals. Material and methods. One-time sensitization of tadpoles (subcutaneously into the ear) was performed according to
О. I. Hrushka +2 more
doaj +1 more source