Results 111 to 120 of about 743,133 (291)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
THE FIRST SEVERE ACUTE RESPIRATORY SYNDROME CASE IN RUSSIA
Acta Biomedica Scientifica, 2020 Clinical picture of SARS, dynamics, diagnostics, including laboratory diagnostics (ELISA, PCR), and treating are described.
A. V. Tarasov +5 more
doaj
Building fault detection and diagnostics: Achieved savings, and methods to evaluate algorithm performance [PDF]
, 2020 Fault detection and diagnosis (FDD) represents one of the most active areas of research and commercial product development in the buildings industry. This paper addresses two questions concerning FDD implementation and advancement 1) What are today's ...
Granderson, J, Kramer, H, Lin, G
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Diagnostics Update for the Emerging (If Not Already Widespread) Sexually Transmitted Infection Agent \u3cem\u3eMycoplasma genitalium\u3c/em\u3e: Just About Ready for Prime Time [PDF]
, 2017 Mycoplasma genitalium is an important and emerging agent of sexually transmitted infection in females and males, carrying the potential for postinfection genital tract sequelae.
Erik, Munson
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Acta Biomedica Scientifica, 2012 The results of yersinioses microbiological monitoring in Novosibirsk Region are presented and introduction of a quality management system in activities of a laboratory of especially dangerous infections is experienced.
T. V. Karimova +5 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A portable device for nucleic acid quantification powered by sunlight, a flame or electricity. [PDF]
, 2018 A decentralized approach to diagnostics can decrease the time to treatment of infectious diseases in resource-limited settings. Yet most modern diagnostic tools require stable electricity and are not portable.
Cesarman, Ethel +8 more
core +1 more source