Results 31 to 40 of about 1,377,526 (260)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Student-centered learning in an engineering course with project-integrated laboratory experiment

open access: yesHögre Utbildning, 2020
In this paper we discuss and present results from the pedagogical development of an advanced-level undergraduate electrical engineering course at Uppsala University, where a new laboratory experiment was implemented.
Jennifer Leijon   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Laboratory experiment in psychology

open access: yesRUDN Journal of Psychology and Pedagogics, 2011
The characteristic of the experimental method in psychology is given. The stages of the making and development, and also the place of the laboratory experiment in modern Russian psychology are considered.
V А Barabanschikov
doaj  

Bioelectrical synchronization of Picea abies during a solar eclipse

open access: yesRoyal Society Open Science
Regular light–dark cycles greatly affect organisms, and events like eclipses induce distinctive physiological and behavioural shifts. While well documented in animals, plant behaviour during eclipses remains largely unexplored.
Alessandro Chiolerio   +6 more
doaj   +1 more source

The LUNA experiment at Gran Sasso Laboratory

open access: yesEPJ Web of Conferences, 2014
Accurate knowledge of thermonuclear reaction rates is a key issue in nuclear astrophysics since it is important for understanding the energy generation, neutrino production and the synthesis of the elements in stars. Cross-section measurements are mainly
Guglielmetti Alessandra
doaj   +1 more source

INFLUENCE OF RAINFALL PRECIPITATION ON THE DEFORMATION OF THE RIVER BANK CHANNELS IN PERMAFROST

open access: yesЛëд и снег, 2015
We studied in the lab the interaction of river runoff from frozen soil, simulating the upper, active-layer, changing the thermal (warming) and mechanical (impact of rain) external influences.
I. I. Gritsuk   +4 more
doaj   +1 more source

Modelling vertical concentration distributions of solids suspended in turbulent visco-plastic fluid

open access: yesJournal of Hydrology and Hydromechanics, 2021
Vertical concentration distributions of solids conveyed in Newtonian fluids can be modelled using Rouse-Schmidt type distributions. Observations of solids conveyed in turbulent low Reynolds number visco-plastic carriers, suggest that solids are more ...
Matoušek Václav   +2 more
doaj   +1 more source

Predicting Trustworthiness Across Cultures: An Experiment

open access: yesFrontiers in Psychology, 2021
We contribute to the ongoing debate in the psychological literature on the role of “thin slices” of observable information in predicting others' social behavior, and its generalizability to cross-cultural interactions. We experimentally assess the degree
Adam Zylbersztejn   +4 more
doaj   +1 more source

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