Results 71 to 80 of about 1,253,203 (304)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Clinical laboratory COVID-19 response call : November 16, 2020 [PDF]
CDC\u2019s Division of Laboratory Systems (DLS) convenes regular calls with clinical laboratories to discuss the nation\u2019s clinical laboratory response to coronavirus disease (COVID-19).
core
Multi-Scale Attentive Interaction Networks for Chinese Medical Question Answer Selection
IEEE Access, 2018 The past few years have witnessed a trend that the deep learning techniques have been increasingly applied in healthcare due to the explosive growth of big data.
Sheng Zhang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Evaluations of Similarity Measures on VK for Link Prediction
Data Science and Engineering, 2018 Recommender system is one of the most important components for many companies and social networks such as Facebook and YouTube. A recommendation system consists of algorithms which allow to predict and recommend friends or products. This paper studies to
JooYoung Lee, Rustam Tukhvatov
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Implementation of a Laboratory Information System in a Simulated Laboratory
American Society for Clinical Laboratory Science, 2017 Electronic health records are the principal method of storing patient health data. Laboratory Information Systems (LIS), a portion of the EHR, are the main avenue for laboratory staff to store data and provide laboratory results to health care providers. This paper examines the implementation of an LIS in an institution where simulated laboratories are
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Empirical Wavelet Transform Based ECG Signal Filtering Method
Journal of Electrical and Computer EngineeringThe electrocardiogram (ECG) is a diagnostic tool that provides insights into the heart’s electrical activity and overall health. However, internal and external noises complicate accurate heart issue diagnosis.
S. Elouaham +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source