Results 71 to 80 of about 26,283,235 (262)
Journal of Innovation in Health Informatics, 2004 This paper describes the uptake and usage by a group of general medical practices in Tayside, Scotland of a novel system designed to give rapid access to laboratory results in primary care.
Deborah Clark +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Laboratory communications toolkit : a resource to create meaningful messages [PDF]
Communicating complex laboratory information to various audiences, including individuals who may not have a laboratory background, is challenging.Clinical and public health laboratories can use this toolkit to translate complex information into user ...
core
Informatization of activity eco-analysis laboratory petrochemical complex
Тонкие химические технологии, 2014 In the article the environmental management system at the enterprises of the petrochemical complexes and ecoanalytical laboratory activities as a part of it are considered.
M. V. Bayukin +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Complex Systems Informatics and Modeling QuarterlyEffective alignment of institutional processes with digital technologies is imperative for enterprises, including those in healthcare. Unfortunately, in the context of health laboratories, the scope and complexity of existing digital health interventions
Agnes Nakakawa +6 more
doaj +1 more source
Multi-Scale Attentive Interaction Networks for Chinese Medical Question Answer Selection
IEEE Access, 2018 The past few years have witnessed a trend that the deep learning techniques have been increasingly applied in healthcare due to the explosive growth of big data.
Sheng Zhang +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source