Results 61 to 70 of about 4,046,127 (288)

Uncertainty of measurement in laboratory medicine [PDF]

Journal of Medical Biochemistry, 2018
An adequate assessment of the measurement uncertainty in a laboratory medicine is one of the most important factors for a reliable interpretation of the results.
Milinković Neda, Ignjatović Svetlana, Šumarac Zorica, Majkić-Singh Nada   +3 more
doaj  

Adequate enrichment of extracellular vesicles in laboratory medicine

Interdisciplinary Medicine, 2023
Extracellular vesicles (EVs) and their clinical applications have been recognized as one of the most fast‐growing and promising fields. Numerous groups including us have expressed their concerns on the idea of isolating “pure” EVs for different purposes,
Limin Zhang, Wencui Ma, Xinyi Gan, Wanyu Chen, Jiahui Guo, Yizhi Cui, Tong Wang   +6 more
doaj   +1 more source

DRD4 genotype predicts longevity in mouse and human [PDF]

, 2013
Longevity is influenced by genetic and environmental factors. The brain's dopamine system may be particularly relevant, since it modulates traits (e.g., sensitivity to reward, incentive motivation, sustained effort) that impact behavioral responses to ...
Barnett Jr., Jeffrey C., Chen, Chuansheng, Ciobanu, Valentina, Corrada, Maria M., Dong, Qi, Grady, Deborah L., Grandy, David, Kawas, Claudia H., Moyzis, Alexandra G., Moyzis, Robert K., Napoli, Anthony, Rubinstein, Marcelo, Shustarovich, Diana, Thanos, Panayotis K., Volkow, Nora D., Wang, Eric, Wang, Gene-Jack   +16 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Diagnostic error reduction in the United States and Italy through the intervention of diagnostic management teams [PDF]

, 2018
A major challenge to most countries is the growing cost of healthcare. The cost of laboratory testing is approximately 3% of the total clinical costs.
Adriana Berumen Velazquez, Michael Laposata, Roberto Verna   +2 more
core  

Baixas temperaturas e risco de morte súbita cardíaca na esquizofrenia: desvendando um novo calcanhar de Aquiles? [PDF]

, 2008
Universidade Federal de São Paulo (UNIFESP) Laboratory of Experimental NeurologyUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Department of PhysiologyUniversidade de São Paulo School of Medicine Department and Institute of ...
ARIDA, Ricardo M, CAVALHEIRO, Esper A, CYSNEIROS, Roberta M, GATTAZ, Wagner F, SCORZA, Fulvio A   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Accreditation in clinical laboratories [PDF]

, 2010
At the beginning of the 21st century there are defined priorities in laboratory medicine such as laboratory automation, laboratory consolidation, molecular diagnostics, and accreditation of laboratories aiming to improve the quality of patient care ...
Tomáš Zima
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Using the failure mode and effects analysis model to improve parathyroid hormone and adrenocorticotropic hormone testing

Risk Management and Healthcare Policy, 2016
Racheli Magnezi,1 Asaf Hemi,1 Rina Hemi2 1Department of Management, Public Health and Health Systems Management Program, Bar Ilan University, Ramat Gan, 2Endocrine Service Unit, Sheba Medical Center, Tel Aviv, Israel Background: Risk management in health
Magnezi R, Hemi A, Hemi R
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