Results 211 to 220 of about 18,259,704 (253)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Long-Term Mortality in Diabetic Foot Disease is Higher Than That of Overall Cancer: Results From Three International Cohorts. [PDF]

Diabetes Metab Res Rev
Zeng Q, Tang Z, Chen X, Zhan L, Balasubramanian V, Chen Z, Du M, Zhang Q, Lian F, Zhang X, Liang Q, Zhao W, Li X, Zhang M, Li Q, Yang S, Hu J, Cheng Q, Shen H.   +18 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Author Correction: A data-centric approach to detecting and mitigating demographic bias in pediatric mental health text. [PDF]

Commun Med (Lond)
Ive J, Bondaronek P, Yadav V, Santel D, Glauser T, Strawn JR, Agasthya G, Tschida J, Choo S, Chandrashekar M, Kapadia AJ, Pestian J.   +11 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Safety and efficacy of the automated liquid-phase embryo storage, Hatchferti: a pilot study. [PDF]

PeerJ
Meng Y, Zhou H, Bai Y, Gao K, Jiang J, Zhou X, Zeng M, Mao Y, Wang C, Liu J, Chen Y, Li L.   +11 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

SelO-mediated nicotinamide adenine dinucleotide hydrolysis and its implications for metabolic therapies. [PDF]

Clin Transl Med
Zhang T, Wang T, Fu Y.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Mapping the Evolution of Diagnostic Research on <i>Mycoplasma pneumoniae</i>: A Bibliometric Analysis (1980-2025). [PDF]

Pathogens
Wu M, Wang J, Xie Z, Xiang Y, Yao C, Liu M, Shang Y, Li C, Ma X, Tuo W, Du H, Huang L, Cai Q.   +12 more
europepmc   +1 more source