Results 141 to 150 of about 8,970,804 (217)

Tractor Testing; Test Track

open access: yes
Checking the dirt track after a crawler tractor had been tested.
Nebraska Tractor Test Laboratory
core  

Tractor Testing; Drawbar Testing; Massey Harris

open access: yes, 1948
"Getting ready to start drawbar test no. 403. Massey-Harris 22 RT." The Massey-Harris 22RT is towing the Adams test car.
Nebraska Tractor Test Laboratory
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tractor Testing; Drawbar; Caterpillar

open access: yes, 1949
D-8 Caterpillar being tested on the dirt track before 1956. Front view of Caterpillar crawler rounding the curve in the test track followed by the test car and six other tractors.
Nebraska Tractor Test Laboratory
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Demonstration; Kubotas after test

open access: yes, 1985
Three Kubota tractors parked side by side after finishing test. A Case tractor is at the end of the row. The tractors include a Kubota L3750 from test 1555, a Kubota L4150 from test 1556, and a Kubota M8950DT from test 1557.
Nebraska Tractor Test Laboratory
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Workshops and Classes

open access: yes, 1948
Veteran trainees visiting test lab during test no. 404. Side view of an Oliver Row Crop 77 HC on the test track towing the Adams test car. Veterans are seated and standing on the two load tractors (a rather unsafe practice)
Nebraska Tractor Test Laboratory
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Tractor Testing; Drawbar Testing; Oliver

open access: yes, 1948
"Test no. 404. 10 hour test." Bird's eye view showing the Oliver Row Crop 77HC being driven around a curve in the test track.
Nebraska Tractor Test Laboratory
core  

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