Results 41 to 50 of about 1,142,944 (309)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Assisting Laboratory Management Based on Network Big Data Mining Technology

open access: yesJournal of Function Spaces, 2022
In today’s big data context, the composition of virtual networks is becoming increasingly complex, so it is neither easy nor difficult to strengthen the control of network security issues.
Yonghua Xu
doaj   +1 more source

Lessons taught and learned from the operation of the solar energy e-learning laboratory [PDF]

open access: yes, 2009
The solar energy e learning laboratory (solar e-lab) in Cyprus is a good example of a web-based, remote engineering laboratory. It comprises a pilot solar energy conversion plant which is equipped with all necessary instrumentation, data acquisition, and
Eleftheriou, Polyvios   +1 more
core   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Dual-Chirp Photonics-Based Radar for Distance and Velocity Measurement Based on Compressive Sensing

open access: yesIEEE Photonics Journal, 2022
We proposed a dual-chirp microwave photonic radar based on compressive sensing for distance and velocity measurement. This radar can generate different chirp linear frequency modulated (LFM) signals using a dual-parallel Mach-Zehnder modulator (DPMZM ...
Yujiao Ding   +7 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Laboratory and field partial discharge measurement in HVDC power cables [PDF]

open access: yes, 2015
A range of experimental and field measurements of partial discharge (PD) activity under high voltage direct current (HVDC) conditions have been conducted with the goal of developing effective monitoring techniques for PD in HVDC cables and ancillary ...
Awodola, Joseph   +9 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Knowledge-Driven Manufacturing Process Innovation: A Case Study on Problem Solving in Micro-Turbine Machining

open access: yesMicromachines, 2021
Micromachining techniques have been applied widely to many industrial sectors, including aerospace, automotive, and precision instruments. However, due to their high-precision machining requirements, and the knowledge-intensive characteristics of ...
Dong Zhang   +6 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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