Results 101 to 110 of about 154,653 (347)

Combined Reinforcement Learning via Abstract Representations

open access: yes, 2018
In the quest for efficient and robust reinforcement learning methods, both model-free and model-based approaches offer advantages. In this paper we propose a new way of explicitly bridging both approaches via a shared low-dimensional learned encoding of ...
Bengio, Yoshua   +3 more
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Clinical features of benign paroxysmal positional vertigo Vertigem posicional paroxística benigna: caracterização clínica

open access: yesBrazilian Journal of Otorhinolaryngology, 2009
Benign paroxysmal positioning vertigo (BPPV) is considered as the most common vestibular disease. AIM: to evaluate the age, gender, type and site of the lesion, association with other vestibular diseases, progression, and recurrence in these patients ...
Mariana Azevedo Caldas   +4 more
doaj   +1 more source

Some considerations of the performance of two honeycomb gas path seal material systems [PDF]

open access: yes
A standard Hastelloy-X honeycomb material and a pack aluminide coated honeycomb material were evaluated as to their performance as labyrinth seal materials for aircraft gas turbine engines.
Bill, R. C., Shiembob, L. T.
core   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

NIR‐Triggered Upconversion‐Perovskite Heterostructures for Non‐Genetic, Implant‐Free Optoelectronic Neuromodulation

open access: yesAdvanced Science, EarlyView.
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang   +19 more
wiley   +1 more source

Time and Consciousness in Three Works by Jorge Luis Borges

open access: yesИбероамериканские тетради
This paper analyzes the concepts of time and consciousness in three works by Jorge Luis Borges. In «The Garden of Forking Paths», the phenomenon of a rhizomorphic labyrinth produces a limitless net of times, forking, converging and parallel to each other.
M. S. Burak
doaj   +1 more source

Le Tanger expérimental de William Burroughs

open access: yesItinéraires, 2013
It is in Tangier, town where was written Naked lunch, that William Burrroughs really became a writer. My hypothesis is that this town, with its specific topography and its status of international zone, induced a crystallization of the writing. Tangier is
Xavier Garnier
doaj   +1 more source

Hemorrhagic Labyrinthitis [PDF]

open access: yesEar, Nose & Throat Journal, 2000
E, Palacios, G, Valvassori
openaire   +2 more sources

Home - About - Disclaimer - Privacy