Results 101 to 110 of about 173,668 (337)

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

open access: yesAdvanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du   +17 more
wiley   +1 more source

Influence of labyrinth orientation relative to gravity on responses elicited by stimulation of the horizontal semicircular canals [PDF]

open access: yes
Gravity labyrinth orientation influence on responses from stimulation of horizontal semicircular ...
Correia, M. J., Guedry, F. E., Jr.
core   +1 more source

Precipitating Ordered Skyrmion Lattices from Helical Spaghetti

open access: yes, 2018
Magnetic skyrmions have been the focus of intense research due to their potential applications in ultra-high density data and logic technologies, as well as for the unique physics arising from their antisymmetric exchange term and topological protections.
Borchers, Julie A.   +10 more
core   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

open access: yesAdvanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang   +10 more
wiley   +1 more source

Biophysical evaluation of the human vestibular system Semiannual status report, 1 Jul. - 31 Dec. 1966 [PDF]

open access: yes
Physical properties of labyrinth fluids in human vestibular ...
Meiry, J. L., Young, L. R.
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

“The Maze Factor” Vs. “The Solar Eye”: Identities of Walkers and Watchers [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2016
This paper will aim to investigate Joyce’s Ulysses, the paradigmatic urban novel, in juxtaposition with Huxley’s dystopian Brave New World and Alasdair Gray’s ambiguous Lanark on the theoretical basis of modern urban planning, environmental psychology,
Marija Spirkovska
doaj  

Theory and measurements of labyrinth seal coefficients for rotor stability of turbocompressors [PDF]

open access: yes
The prediction of rotordynamic coefficients for gas seals is achieved with the aid of a two-volume bulk flow model based on turbulent rotationally symmetric 3D flow calculations including swirl flow.
Syssmann, H. R.
core   +1 more source

On certain families of planar patterns and fractals

open access: yes, 2017
This survey article is dedicated to some families of fractals that were introduced and studied during the last decade, more precisely, families of Sierpi\'nski carpets: limit net sets, generalised Sierpi\'nski carpets and labyrinth fractals.
Cristea, Ligia L.
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

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