Results 121 to 130 of about 173,668 (337)

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source

A heterotopic perception of ‘wall’ in psychological thriller films: a place, a labyrinth and a panoptic power

Cogent Arts & Humanities
A wall is often viewed simply as a structure that divides and isolates different worlds, spaces, or places. However, an alternative perspective, known as the heterotopic point of view, suggests that a wall can be seen as a place.
Lama B. Abuhassan, Mays M. Dweiri
doaj   +1 more source

Hemorrhagic Labyrinthitis [PDF]

Ear, Nose & Throat Journal, 2000
E, Palacios, G, Valvassori
openaire   +2 more sources

THE LABYRINTH OF PHILOSOPHY IN ISLAM [PDF]

, 2010
This paper focuses on the methodological issues related to the obstacles and potential horizons of approaching the philosophical traditions in Islam from the standpoint of comparative studies in philosophy, while also presenting selected case-studies ...
El-Bizri, Nader
core   +1 more source

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

Advanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi, Huiquan Shan, Haoping Wang, Xi Guo, Houcheng Li, Bo Han, Senlin Zhu, Fei Wang, Guanghui Tan, Zhannur Niyazbekova, Jilong Ren, Yaqi Zhou, Qi Zhang, Weijie Zheng, Minghui Jia, Ao Zhang, Xuesha Cao, Huizeng Sun, Dongxiao Sun, Lingzhao Fang, Yi Zheng, Xihong Wang, Yu Jiang   +22 more
wiley   +1 more source

The labyrinth as a symbol of life: A journey with God and chronic pain

HTS Teologiese Studies/Theological Studies, 2017
This article is written in the style and method of an autoethnography that focuses on the author’s spiritual journey with God while living with chronic pain. The labyrinth is used as a metaphor and spiritual tool to describe this journey.
Lishje Els
doaj   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Irreversible transformation of ferromagnetic ordered stripe domains in single-shot IR pump - resonant X-ray scattering probe experiments

, 2015
The evolution of a magnetic domain structure upon excitation by an intense, femtosecond Infra-Red (IR) laser pulse has been investigated using single-shot based time-resolved resonant X-ray scattering at the X-ray Free Electron laser LCLS. A well-ordered
Baumier, Cédric, Bergeard, Nicolas, Boeglin, Christine, Delaunay, Renaud, Eisebitt, Stefan, Fortuna, Franck, Geilhufe, Jan, Graves, Catherine, Günther, Christian M., Jaouen, Nicolas, Krupin, Oleg, López-Flores, Víctor, Lüning, Jan, Minitti, Michael P., Robinson, Joe, Schaffert, Stefan, Scherz, Andreas, Schlotter, William F., Schneider, Michael, Tortarolo, Marina, Tudu, Bharati, Turner, Joshua J., Wang, Tianhan, Wu, Benny   +23 more
core   +3 more sources

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Strategic programming on graph rewriting systems

, 2010
We describe a strategy language to control the application of graph rewriting rules, and show how this language can be used to write high-level declarative programs in several application areas.
Andy Schürr, Arend Rensink, Bruno Courcelle, Claudia Ermel, César Muñoz, Daniel Balasubramanian, Detlef Plump, Detlef Plump, Eelco Visser, Emilie Balland, Franz Baader, Georges Gonthier, H.P. Barendregt, Hélène Kirchner, Ian Mackie, Ian Mackie, John Mccarthy, Klaus Barthelmann, M. Fernández, Maribel Fernández, Maribel Fernández, O. Andrei, Oana Andrei, Oana Andrei, Olivier Namet, Peter Borovansky, Peter Borovanský, Rubino Geiß, Ulrich Nickel, Yves Lafont   +29 more
core   +2 more sources