Journal of the Science of Food and Agriculture, EarlyView.Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho +6 more
wiley +1 more source
Deficient Visuospatial Incidental and Intentional Memory in Cognitively Healthy Middle-Aged First-Degree Descendants of Alzheimer's Disease Patients. [PDF]
Brain SciÁlvarez-Huante CG +6 more
europepmc +1 more source
Balance Disorders in Young and Middle‐Aged Adults: NHANES, 2001–2004 and 2021–2023
The Laryngoscope, EarlyView.This study presents nationally‐representative estimates from two health exam surveys, NHANES 2001–2004 and 2021–2023. In the two decades between test periods, scores on the modified Romberg screening test for balance function demonstrated significantly better age‐specific performance in 2021–2023.
Howard J. Hoffman +8 more
wiley +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
The Laryngoscope, EarlyView.In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
TNF-α impairs the stria vascularis by inducing pericyte apoptosis via the NF-κB pathway in gentamicin-induced hearing loss. [PDF]
J NeuroinflammationLi G +6 more
europepmc +1 more source
The Laryngoscope, EarlyView.Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares +5 more
wiley +1 more source
Maternal high-fat, high-sucrose diet-induced excess adiposity is linked to placental hypoxia and disruption of fetoplacental immune homeostasis in late gestation†. [PDF]
Biol ReprodBellissimo CJ +8 more
europepmc +1 more source
Synchrotron‐Based Deep Learning Network of the Inner Ear: Development and Expert Validation
The Laryngoscope, EarlyView.A deep learning network to automatically segment the inner ear from preoperative clinical scans was developed using synchrotron‐radiation phase contrast imaging (SR‐PCI). On an unseen test set, the network significantly outperformed seven expert otologists/radiologists, the mean expert segmentation, and a simultaneous truth and performance level ...
Ashley Micuda +11 more
wiley +1 more source
Peer Action Coordination in Middle Childhood: A Replication Null Finding on Emotion Understanding and Inhibitory Control. [PDF]
Behav Sci (Basel)Barresi G +4 more
europepmc +1 more source
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source