Results 131 to 140 of about 2,149,670 (310)
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen +7 more
wiley +1 more source
River and canyon walls in Labyrinth/Stillwater Canyons on Green River, Eggert-Hatch River Expedition ...
Eggert, Charles, 1918-2005
core
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
The phenomenon of the labyrinth in architecture and culture is viewed together with its origin, typology, meanings and mythopoetic content. The image of the labyrinth goes through the centuries of architectural history, still remaining a virtual hero ...
Petr Kapustin
core +2 more sources
Rotordynamic Coefficients for Labyrinth Gas Seals: Single Control Volume Model [PDF]
Vatta, Furio +3 more
core +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Infectious Diseases Pathology Branch [PDF]
IDPB conducts investigations and studies of infectious diseases of unknown cause or origin to help identify previously unrecognized or new infectious agents.CS256582-APublication date from document properties.Infectious-Disease-Pathology-factsheet-7-2015.
core
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Background Enteric infectious diseases claim more than 1 million lives annually and are among the top ten causes of death in children younger than 5 years.
GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators +1 more
core

