Results 241 to 250 of about 9,324,522 (375)

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe   +9 more
wiley   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, EarlyView.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Tui Na Acupressure Modulates Treg Immunosuppression via FoxP3/mTORC1 Signalling in ALS Mice

open access: yesImmunology, EarlyView.
The proposed mechanism by which Tui Na acupressure improves motor and cognitive dysfunction in ALS mice by activating the FoxP3/mTORC1 pathway. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease driven by neuroinflammation, where regulatory T cell (Treg) dysfunction exacerbates immune imbalance.
Jie Han   +7 more
wiley   +1 more source

Spontaneous SSCD Auto-Plugging: Clinical, Electrophysiological and Radiological Evidence. [PDF]

open access: yesJ Clin Med
Reynard P   +5 more
europepmc   +1 more source

Sleep Deprivation Alters T Cell Dynamics: Melatonin as a Restorative Agent

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep is an essential physiological function regulated by circadian rhythm and homeostatic regulation for emotional and physical health. Conversely, sleep deprivation (SD) is associated with weakened immune system function and overall health, which potentially leads to chronic diseases such as heart disease and diabetes.
Hilal Öztürk   +8 more
wiley   +1 more source

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