Results 151 to 160 of about 3,440 (255)

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi   +14 more
wiley   +1 more source

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko   +14 more
wiley   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

Surgical approaches to inner ear therapies. [PDF]

open access: yesCurr Opin Otolaryngol Head Neck Surg
Creber N, Bance M.
europepmc   +1 more source

Impact of Female Mating Status on Male Courtship Behaviour in a Sexually Cannibalistic New Zealand Fishing Spider

open access: yesEthology, EarlyView.
Scoring of male courtship behaviour in Dolomedes minor revealed no effect of female mating status on courtship duration or sequence structure, but males delayed the initiation of courtship when encountering previously mated females. ABSTRACT The evolution of male courtship rituals has traditionally been attributed to female mate selection, but may also
Bastien E. Clémot   +2 more
wiley   +1 more source

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