Results 91 to 100 of about 514,885 (296)

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan, Han‐Jung Kuo, Yu‐Chieh Lin, Yen‐An Lu, Wei‐Shou Hu, Qi Zhang   +5 more
wiley   +1 more source

WATER WITHIN LIGHTWEIGHT AGGREGATE CONCRETE AND ITS RELATION TO AUTOGENOUS SHRINKAGE [PDF]

, 2006
Autogenous shrinkage of lightweight aggregate concrete (LAC) has been investigated with the aims of studying if water within LAC is effective in preventing autogenous shrinkage as suggested by Bentz’s model.
Kristiawan, S A, Sangadji, Senot
core  

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Les espèces exotiques dans les lacs français métropolitains

Sciences, Eaux & Territoires
Les invasions biologiques sont à la fois une cause et une conséquence des changements écologiques visibles au sein des lacs français. Après avoir clarifié les subtilités sémantiques liées à la définition des espèces exotiques et les mécanismes ...
Victor FROSSARD, Stéphan JACQUET, Cécile CHARDON, Isabelle DOMAIZON, Julien DUBLON, Jean GUILLARD, Alexandre LEVALLOIS, Clément RAUTUREAU, Jean-Claude RAYMOND, Hervé ROGISSART, Chloé VAGNON, Marine VAUTIER, Vincent BERTRIN   +12 more
doaj   +1 more source

Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis

Critical Care, 2017
Background A decrease in blood lactate levels (Lac) >10% during the first hours of resuscitation in sepsis is associated with better outcomes, but the mechanisms are unclear.
Thiago Domingos Corrêa, Adriano José Pereira, Sebastian Brandt, Madhusudanarao Vuda, Siamak Djafarzadeh, Jukka Takala, Stephan Mathias Jakob   +6 more
doaj   +1 more source

Teacher–Student Relationship Quality as a Mediator in the Association of Parent–Child Communication With Adolescent Bullying Perpetration and Substance Use: Evidence From the 2017/2018 HBSC Study

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Bullying perpetration and substance use are two prevalent and concerning forms of delinquent behavior worldwide. Although parent–child communication has been theorized to reduce adolescents' involvement in these behaviors, empirical evidence remains mixed.
Hang Zhou, Ji‐Kang Chen
wiley   +1 more source

Study of the Operation of Lead–Acid Battery Electrodes Under Hybrid Battery–Electrolyzer Cycling Profiles

Batteries
Flooded lead–acid batteries start producing oxygen and hydrogen during the final stages of charge and subsequent overcharge. The collection of the hydrogen produced allows for an increase in overall energy efficiency and transforms the system into a ...
Elisabeth Lemaire, Lionel Serra, Catherine Arnal, Florence Ardiaca, Daniel Monchal, Nicolas Guillet, Angel Kirchev   +6 more
doaj   +1 more source

Artificial intelligence in enzyme catalysis: Emerging trends and applications in biocatalyst engineering

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales, Francisco Izaias da Silva Aires, Paulo Gonçalves de Sousa Junior, Calebe Da Rocha Silva, Emanuel Lino Rodrigues, Maria Cristiane Martins de Souza, José C. S. dos Santos   +6 more
wiley   +1 more source

Optical Polarization of 52 Radio-Loud QSOs and BL Lac Objects

, 1998
Polarization measurements are presented for 52 radio-loud QSOs and BL Lac objects. For 9 highly polarized (p >3%) AGN, these are the first published polarization measurements.
Beverley J. Wills, Kidger M. R., Mead A. R. G., Natarajan Visvanathan, Rusk R., Scarpa R., Stickel M., Wagner S. J., Wilkes B. J.   +8 more
core   +1 more source

Exploring wave propagation behaviors in rock: A grain‐based perspective on mineral structures

Deep Underground Science and Engineering, EarlyView.
This study investigates wave propagation in rock at the grain scale using a grain‐based model, revealing that mineral elastic modulus significantly influences wave attenuation while grain size and distribution have limited effects. A novel peak particle velocity attenuation prediction model is proposed and validated for grain‐scale wave propagation ...
Zhiyi Liao, Jiachen Xu, Kai Zhang, Changtai Zhou   +3 more
wiley   +1 more source