Results 151 to 160 of about 7,921 (224)

Physiologically Constrained Deep Learning in Physiologically Based Pharmacokinetic Modeling: Virtual Patient Generation, Machine-Learned Scaling Laws, and Pediatric Precision Dosing. [PDF]

Pharmaceutics
Zhang L, Xu Y.
europepmc   +1 more source

Neuropathic Pain: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Neuropathic pain arises from peripheral nerve injury, central sensitization, neurotransmitter imbalance, neuroimmune activation, and maladaptive circuit remodeling. Clinical phenotyping and multimodal imaging can identify dominant peripheral and central mechanisms.
Yaling Dai, Mengquan Tan, Man Yuan, Huixian Zhou, Qin Xie, Jiling Zeng, Yixin Yang, Xinran He, Siyuan Song   +8 more
wiley   +1 more source

Lacosamide Use After Traumatic Brain Injury: A Scoping Review. [PDF]

Cureus
Taniguchi H, Yamada S.
europepmc   +1 more source

Concentration-to-dose ratio as a predictor of lacosamide efficacy in Chinese children with epilepsy: a single-center retrospective cohort study. [PDF]

Front Pharmacol
Du Z, Wang Y, Nie G, Liu M, Li Y, Wang J.   +5 more
europepmc   +1 more source

Advances in Sodium Channel Modulation in Epilepsy Therapy: Focus on Eslicarbazepine, Lacosamide and Cenobamate. [PDF]

Biomedicines
Rudkowska M, Mołdoch J, Wronikowska-Denysiuk O, Agacka-Mołdoch M, Pradiuch A, Wojtunik-Kulesza K.   +5 more
europepmc   +1 more source

Efficacy and Safety of Clobazam as Adjunctive Therapy for Pediatric Patients with Refractory Epilepsy in Xinjiang, China: A Multicenter Real-World Study. [PDF]

Drug Des Devel Ther
Zhao T, Li HJ, Zhang HL, Yu LH, Yu J, Sun Y, Cheng LF.   +6 more
europepmc   +1 more source

Case Report: Leukoencephalopathy with calcifications and cysts caused by novel biallelic SNORD118 variants in a childhood-onset patient with long-term follow-up. [PDF]

Front Neurosci
Tian D, Chen B, Li W, Wang J, Zhang Z.
europepmc   +1 more source

Effectiveness of prophylactic administration of new-generation antiepileptic drugs for prevention of seizures following surgical clipping in patients with aneurysmal subarachnoid hemorrhage. [PDF]

BMC Neurol
Kayahara T, Sakurada K, Mochizuki Y, Maeda T, Take Y, Teranishi A, Kurita H.   +6 more
europepmc   +1 more source

Pharmacological Incongruity of Lacosamide in the Management of Delirium Complicated by Ileus. [PDF]

Neuropsychopharmacol Rep
Nagamine T.
europepmc   +1 more source

Management of epilepsy in the brain tumour patient: Current concepts and practical approaches. [PDF]

Clin Med (Lond)
Rees J.
europepmc   +1 more source