Results 61 to 70 of about 4,908 (189)

Synergistic roles of aquaporin 5 and intra‐ and extracellular carbonic anhydrases in promoting CO2 diffusion across the Xenopus oocyte plasma membrane

The Journal of Physiology, Volume 604, Issue 3, Page 1174-1234, 1 February 2026.
Abstract figure legend Fick's law: JCO2=PM*,CO2±hAQP5·([CO2]os±bCA−[CO2]is±hCAII)TransmembraneCO2gradient${J}_{{\mathrm{CO}}_{2}}=\underset{\pm \mathrm{hAQP}5}{\underset{}{{P}_{\mathrm{M}^\ast ,{\mathrm{CO}}_{2}}}}\, \cdot \underset{\mathrm{Transmembrane}\ {\mathrm{CO}}_{2}\ \mathrm{gradient}}{\underset{}{(\underset{\pm \mathrm{bCA}}{\underset ...
Deng‐Ke Wang, Fraser J. Moss, Walter F. Boron   +2 more
wiley   +1 more source

Re‐evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract The present opinion deals with the re‐evaluation of sucralose (E 955) as food additive and with the safety of a proposed extension of use in food category (FC) 7.2 ‘Fine bakery wares’. Based on the available data, no safety concerns arose for genotoxicity of sucralose (E 955) and its impurities and degradation products.
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Monika Batke, Antonios Douros, James Chipman, Riccardo Crebelli, Peter Fürst, Thorhallur Halldorsson, Manuela Mirat, Alicja Mortensen, Matthew Wright, Oliver Lindtner, Stefania Barmaz, Consuelo Civitella, Zsuzsanna Horvath, Sara Levorato, Elena Mazzoli, Josef Daniel Rasinger, Ana Maria Rincon, Camilla Smeraldi, Alexandra Tard, Federica Lodi   +36 more
wiley   +1 more source

The Microbiome Modulates Corneal Wound Healing via the Induction of Cholesterol Sulfotransferase Pathway

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Antibiotic‐mediated disruption of commensal microbiota increases corneal cholesterol sulfate (CS) production through upregulation of SULT2B1, resulting in impaired corneal epithelial wound healing. Elevated CS suppresses neutrophil recruitment and epithelial cell migration via inhibition of the DOCK2–Rac pathway.
Mamoru Ogawa, Yosuke Isobe, Haruki Uchino, Masatoshi Hirayama, Tamotsu Kato, Kazuno Negishi, Makoto Arita   +6 more
wiley   +1 more source

Polyhexanide, Povidone‐Iodine, and Hypochlorous Acid Show High In Vitro Antimicrobial Efficacy Against Pathogens Commonly Associated With Equine Infectious Keratitis

Veterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Objective To determine the in vitro antimicrobial activity of specific antiseptics against common equine ocular surface pathogens. Methods Staphylococcus aureus (S. aureus) (n = 12), Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) (n = 9), Enterobacter hormaechei (E. hormaechei) (n = 6), and Bacillus cereus (B.
Leonie Maria Stolle, Hilke Oltmanns, Jessica Meißner, Frederik Heun, Ann‐Kathrin Schieder, Hinrich Tönjes Wolff, Bernhard Ohnesorge, Claudia Busse   +7 more
wiley   +1 more source

Feasibility of treatment planning with HyperArc stereotactic radiosurgery methods for ocular tumors

Journal of Applied Clinical Medical Physics, Volume 26, Issue 12, December 2025.
Abstract Purpose/objectives Currently, ocular disease is primarily managed with COMS plaque brachytherapy. Various stereotactic radiosurgery (SRS) platforms have also been employed, yet widespread access remains a challenge. Herein, we demonstrate the feasibility of using the HyperArc SRS system to provide an additional platform for the treatment of ...
Chase Cochran, Shane McCarthy, William St. Clair, Damodar Pokhrel   +3 more
wiley   +1 more source

Rosemary Essential Oil Microemulsion for Fungal Keratitis Treatment

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT This study investigated the use of Rosmarinus officinalis (rosemary) essential oil in a microemulsion (ME) formulation for the treatment of ocular fungal keratitis, a serious infection that can lead to blindness. The ME was characterized in terms of pH, stability, homogeneity, osmolarity, and other physicochemical properties.
Saulo Ribeiro, Mariana Coelho Moraes, Denise de Oliveira Scoaris, Jovita Eugênia Gazinelli Cruz Madeira, Silvia Ligório Fialho, Carolina Paula de Souza Moreira   +5 more
wiley   +1 more source

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, Volume 31, Issue 12, Page 3323-3335, December 2025.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

Contrast computed tomography dacryocystorhinography identifies nasolacrimal duct obstruction secondary to chronic dental disease in two Chinchilla lanigera

Veterinary Ophthalmology, Volume 28, Issue 6, Page 983-989, November 2025.
Abstract Objective To determine the impact of chronic dental disease on the nasolacrimal duct of chinchillas using contrast CT dacryocystorhinography. Animals Studied Two 12‐year‐old female chinchillas with uni‐ or bilateral ocular discharge and a history of chronic, moderate (Chinchilla 1, one‐year) or severe (Chinchilla 2, three‐years) dental disease.
Erin A. Hisey, Paula Rodriguez, Danielle K. Tarbert, Joanne R. Paul‐Murphy, Carli Hendrickson, Kelsey Brust, David J. Maggs, Brian C. Leonard   +7 more
wiley   +1 more source

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, Volume 8, Issue 9, September 2025.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Mechanistic behaviour and molecular interactions of heat shock protein 47 (HSP47) [PDF]

, 2012
This project involves the study of heat shock protein 47 (HSP47), which is a molecular chaperone crucial for collagen biosynthesis. It exhibits a high degree of sequence homology with members of the serine protease inhibitor (serpin) superfamily, though ...
Abdul Wahab, Mohd Firdaus, Abdul Wahab, Mohd Firdaus   +1 more
core   +1 more source