Results 21 to 30 of about 21,919 (232)

Bioengineered Lacrimal Gland Organ Regeneration in Vivo

Journal of Functional Biomaterials, 2015
The lacrimal gland plays an important role in maintaining a homeostatic environment for healthy ocular surfaces via tear secretion. Dry eye disease, which is caused by lacrimal gland dysfunction, is one of the most prevalent eye disorders and causes ...
Masatoshi Hirayama, Kazuo Tsubota, Takashi Tsuji   +2 more
doaj   +1 more source

Lacrimal Gland Abscess: A Case Report

Case Reports in Ophthalmology, 2023
Introduction: The aim of the study was to report a rare case of lacrimal gland abscess. Case Presentation: A 47-year-old woman noticed upper eyelid swelling on the right side 1.5 months before referral to our service.
Mayari Ito, Aric Vaidya, Steffani Krista Someda, Yasuhiro Takahashi   +3 more
doaj   +1 more source

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

npj Aging and Mechanisms of Disease, 2017
Regenerative medicine: lacrimal gland epithelium in vitro One possible approach to treat dry eye diseases is to transplant lacrimal glands generated in vitro from human embryonic stem cells into patients.
Masatoshi Hirayama, Shigeru B.H. Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K. Goparaju, Atsumi Soma, Yuhki Nakatake, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeto Shimmura, Kazuo Tsubota, Minoru S.H. Ko   +11 more
doaj   +1 more source

Studying the role of thyroid hormone receptor expression in the lacrimal gland in the autoimmune orbitopathy

Oftalʹmologiâ, 2014
Purpose: To explore the role of thyroid hormone’ receptors in the development of the autoimmune process in orbita.Methods: The intraoperative biopsy material of the lacrimal gland obtained from orbital decompression in patients with autoimmune ...
V. G. Likhvantseva, O. A. Gontyurova, E. A. Rudenko, T. N. Saphonova, K. A. Kuzmin, N. Y. Sviridenko   +5 more
doaj   +3 more sources

The value of SPECT/CT imaging of lacrimal glands as a means of assessing the activity of Graves’ orbitopathy

Endocrine Connections, 2022
Background: Graves’ orbitopathy (GO) is an autoimmune disease with mechanical impairment of orbital muscles and lacrimal gland dysfunction. The frequently used methods of assessing GO activity include Clinical Activity Score (CAS), CT, and MRI.
Ru-Xuan Zhao, Ting-Ting Shi, Sha Luo, Yun-Fu Liu, Zhong Xin, Jin-Kui Yang   +5 more
doaj   +1 more source

Data supporting regulating temporospatial dynamics of morphogen for structure formation of the lacrimal gland by chitosan biomaterials

Data in Brief, 2017
The lacrimal gland is responsible for tear synthesis and secretion, and is derived from the epithelia of ocular surface and generated by branching morphogenesis.
Ya-Chuan Hsiao, Tsung-Lin Yang
doaj   +1 more source

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. [PDF]

PLoS Genetics, 2017
The sequential use of signaling pathways is essential for the guidance of pluripotent progenitors into diverse cell fates. Here, we show that Shp2 exclusively mediates FGF but not PDGF signaling in the neural crest to control lacrimal gland development ...
Ankur Garg, Mukesh Bansal, Noriko Gotoh, Gen-Sheng Feng, Jian Zhong, Fen Wang, Ariana Kariminejad, Steven Brooks, Xin Zhang   +8 more
doaj   +1 more source

A Ligation of the Lacrimal Excretory Duct in Mouse Induces Lacrimal Gland Inflammation with Proliferative Cells

Stem Cells International, 2017
The lacrimal gland secretes tear fluids to ocular surface, which plays an indispensable role in maintaining the health of the ocular epithelia and protecting the ocular surface from the external environment.
Ying Liu, Masatoshi Hirayama, Tetsuya Kawakita, Kazuo Tsubota   +3 more
doaj   +1 more source

Unusual Presentation of Lacrimal Gland Pleomorphic Adenoma

Journal of Nepal Medical Association, 2014
The pleomorphic adenoma of lacrimal gland presents as a painless, progressive, slowly growing supero-temporal swelling with variable proptosis. This tumor is usually found in adults and extremely rare in teenage.
Shailesh Mani Pokharel, Ashish Raj Pant, Badri Prasad Badhu, Punam Lavaju, Bhuwan Govinda Shrestha, Meenu Agarwal   +5 more
doaj   +1 more source

Invasive Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland with a Cystadenocarcinoma Component: A Case Report and Review of the Literature

Case Reports in Pathology, 2020
Lacrimal gland neoplasms comprise up to 18% of all orbital masses clinically and histologically. Much of our current core knowledge regarding lacrimal gland tumors stems from prior study of their more common counterparts, the salivary glands.
Vamsee K. Neerukonda, Bryant Carruth, Maria Del Valle Estopinal   +2 more
doaj   +1 more source