Results 81 to 90 of about 513,538 (307)
Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome
PLoS ONE, 2017 Sjögren’s syndrome (SS) is a chronic, autoimmune exocrinopathy that leads to severe dryness of the mouth and eyes. Exocrine function is highly regulated by neuronal mechanisms but little is known about the link between chronic inflammation, innervation ...
F. Chen +5 more
semanticscholar +1 more source
Potential roles of antibodies with different classes in IgG4‐related diseases
Rheumatology &Autoimmunity, EarlyView.This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li +6 more
wiley +1 more source
Pilomatrix carcinoma of the lacrimal caruncle: a case report. [PDF]
, 2020 A 45-year-old man presented with a 3-month history of a mass located in the caruncle of his right eye. An incisional biopsy had been performed one month prior by another specialist, and the histopathology report showed basal cell carcinoma.
Acıkalin, Arbil +4 more
core +1 more source
Invariant NKT cells and rheumatic disease: Focus on primary sjogren syndrome [PDF]
, 2019 Primary Sjogren syndrome (pSS) is a complex autoimmune disease mainly affecting salivary and lacrimal glands. Several factors contribute to pSS pathogenesis; in particular, innate immunity seems to play a key role in disease etiology.
Barbera L. L. +5 more
core +1 more source
Adenocarcinoma of the lacrimal gland: a case report
Journal of Medical Case Reports, 2017 Background Primary ductal adenocarcinomas of the lacrimal gland are very rare. This neoplasm shares some histological and immunohistochemical similarities with salivary duct carcinoma.
Asmae Touil +5 more
doaj +1 more source
Establishing human lacrimal gland cultures with secretory function. [PDF]
PLoS ONE, 2012 PURPOSE: Dry eye syndrome is a multifactorial chronic disabling disease mainly caused by the functional disruptions in the lacrimal gland. The treatment involves palliation like ocular surface lubrication and rehydration.
Shubha Tiwari +6 more
doaj +1 more source
Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization
Rheumatology &Autoimmunity, EarlyView.Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo +7 more
wiley +1 more source
Iatrogenic keratoconjunctivitis sicca in a dog [PDF]
Ciência Rural, 2004 Qualitative and quantitative abnormalities in primary components of the tear can alter the dynamics of the lacrimal film, compromising its function. Lipids, an aqueous fraction and mucoproteins constitute the lacrimal film.
Denise Eliza de Almeida +3 more
doaj +1 more source
Mitochondrial dynamics in autoimmune diseases
Rheumatology &Autoimmunity, EarlyView.Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma +5 more
wiley +1 more source
IgG4-related autoimmune disease : imaging findings [PDF]
, 2013 IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
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