Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome
PLoS ONE, 2017 Sjögren’s syndrome (SS) is a chronic, autoimmune exocrinopathy that leads to severe dryness of the mouth and eyes. Exocrine function is highly regulated by neuronal mechanisms but little is known about the link between chronic inflammation, innervation ...
F. Chen +5 more
semanticscholar +1 more source
Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]
, 2012 Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Hideyuki Okano +12 more
core +1 more source
Dez anos de acompanhamento de uma série de casos de neoplasias epiteliais primárias da glândula lacrimal: características clínicas, tratamento cirúrgico e achados histopatológicos [PDF]
, 2010 PURPOSE: To describe and analyze the features of a cases series of patients with primary epithelial neoplasms of the lacrimal gland, its surgical treatment, and histopathological findings.
Cursino, Sylvia Regina T. +6 more
core +3 more sources
IgG4-related autoimmune disease : imaging findings [PDF]
, 2013 IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
core
Malignancies and immunoglobulin G4‐related disease
Rheumatology &Autoimmunity, EarlyView.Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley +1 more source
An unusual presentation of lacrimal gland pleomorphic adenoma
Revista Brasileira de Oftalmologia, 2013 Tumors of the lacrimal gland are rare in clinical practice. Among all of them, the most common epithelial tumor is the lacrimal gland pleomorphic adenoma, which is a benign indolent tumor that usually affects adults in the third and fourth decades of ...
Josie Naomi Iyeyasu +3 more
doaj +1 more source
Congenital fistulae of the lacrimal gland. [PDF]
British Journal of Ophthalmology, 1980 A 36-year-old man had congenital fistulae of the palpebral lobes of the lacrimal glands, with orifices bilaterally in the intermarginal strip of his upper eyelids near the external canthi. The left fistula was cystic and had become chronically inflamed. Because antibiotic therapy was unsuccessful, excision was necessary.
B.A.E. van der Pol, L.J. Blanksma
openaire +4 more sources
Potential roles of antibodies with different classes in IgG4‐related diseases
Rheumatology &Autoimmunity, EarlyView.This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li +6 more
wiley +1 more source
Pilomatrix carcinoma of the lacrimal caruncle: a case report. [PDF]
, 2020 A 45-year-old man presented with a 3-month history of a mass located in the caruncle of his right eye. An incisional biopsy had been performed one month prior by another specialist, and the histopathology report showed basal cell carcinoma.
Acıkalin, Arbil +4 more
core +1 more source
Invariant NKT cells and rheumatic disease: Focus on primary sjogren syndrome [PDF]
, 2019 Primary Sjogren syndrome (pSS) is a complex autoimmune disease mainly affecting salivary and lacrimal glands. Several factors contribute to pSS pathogenesis; in particular, innate immunity seems to play a key role in disease etiology.
Barbera L. L. +5 more
core +1 more source