Results 71 to 80 of about 155,998 (284)
Advanced Science, Volume 12, Issue 16, April 24, 2025.A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu +10 more
wiley +1 more source
How Do Practitioners Perceive Assurance Cases in Safety-Critical Software Systems? [PDF]
, 2018 Safety-critical software systems are those whose failure or malfunction could result in casualty and/or serious financial loss. In such systems, safety assurance cases (SACs) are an emerging approach that adopts a proactive strategy to produce structuralized safety justifications and arguments.
arxiv +1 more source
Deep Reinforcement Learning-based UAV Navigation and Control: A Soft Actor-Critic with Hindsight Experience Replay Approach [PDF]
arXiv, 2021 In this paper, we propose SACHER (soft actor-critic (SAC) with hindsight experience replay (HER)), which constitutes a class of deep reinforcement learning (DRL) algorithms. SAC is known as an off-policy model-free DRL algorithm based on the maximum entropy framework, which outperforms earlier DRL algorithms in terms of exploration, robustness and ...
arxiv
Advanced Science, Volume 12, Issue 15, April 17, 2025.Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu +8 more
wiley +1 more source
Nasolacrimal Duct Obstruction Caused by Primary Lacrimal Sac Adenocarcinoma [PDF]
, 2019 Background: Primary lacrimal sac tumors are a group of rare, highly malignant group of orbital neoplasms. Early diagnosis is critical, but often delayed, as these tumors are commonly mistaken for comparatively benign conditions.
Brill, Daniel +4 more
core +1 more source
Magnetic resonance dacryocystography: Its role in the diagnosis and treatment plan of lacrimal drainage system obstructions [PDF]
, 2014 Objective: To evaluate the role of magnetic resonance dacryocystography (MR-DCG) technique in patients with obstruction of lacrimal drainage system. Methods: A total of 40 patients who had presented to the ophthalmology clinic were suspected to have ...
Cemil Apaydın +3 more
core +1 more source
Early synapsids neurosensory diversity revealed by CT and synchrotron scanning
The Anatomical Record, EarlyView.Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit +6 more
wiley +1 more source
Classical vs. Retrograde Endoscopic Dacryocystorhinostomy: Analyses and Comparison of the Results. [PDF]
Background: In endoscopic dacryocystorhinostomy (DCR), surgical landmarks such as the maxillary line (ML) and the axilla of the middle turbinate (MT) guide the surgeon in identifying the lacrimal sac.
Aggazzotti Cavazza, Elisa +6 more
core +4 more sources
Meta-SAC: Auto-tune the Entropy Temperature of Soft Actor-Critic via Metagradient [PDF]
arXiv, 2020 Exploration-exploitation dilemma has long been a crucial issue in reinforcement learning. In this paper, we propose a new approach to automatically balance between these two. Our method is built upon the Soft Actor-Critic (SAC) algorithm, which uses an "entropy temperature" that balances the original task reward and the policy entropy, and hence ...
arxiv
Context-Based Soft Actor Critic for Environments with Non-stationary Dynamics [PDF]
arXiv, 2021 The performance of deep reinforcement learning methods prone to degenerate when applied to environments with non-stationary dynamics. In this paper, we utilize the latent context recurrent encoders motivated by recent Meta-RL materials, and propose the Latent Context-based Soft Actor Critic (LC-SAC) method to address aforementioned issues.
arxiv