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Immunocytochemical heterogeneity of lactase-phlorizin hydrolase in adult lactase deficiency
Gastroenterology, 1993Adult lactase deficiency may result either from diminished synthesis of precursor lactase-phlorizin hydrolase (phenotype I deficiency) or from altered posttranslational processing of the precursor protein (phenotype II). The aim of this study was to compare the location of lactase-phlorizin hydrolase along the crypt-villus axis in control with adult ...
V, Lorenzsonn, M, Lloyd, W A, Olsen
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Absorption of nutrients in lactase deficiency
Digestive Diseases and Sciences, 1979The influence of malabsorption of lactose, as a result of primary lactase deficiency, on the absorption of the nutrients in milk was tested in four healthy controls and four subjects with lactase deficiency. An ileal perfusion technique was used to quantify arrival in the ileum of nutrients and a nonabsorbable marker (polyethylene glycol, PEG 4000 ...
J C, Debongnie +3 more
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Congenital and Adult Intestinal Lactase Deficiency
New England Journal of Medicine, 1976Although lactase was identified in mammalian small intestine more than 40 years ago,1 the enzyme was commonly believed to be secreted into intestinal fluid until Crane and his colleagues2 3 4 estab...
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