Results 101 to 110 of about 980,886 (403)

Comparison of d and l-lactate content in cow and camel milk [PDF]

, 2015
Lactate is the product of fermentation of lactose in the digestive tract of milk consumers. The lactate has benef icial effect on health for the regulation of the milk protein digestion and calcium absorption. However, lactate has two stereoisomere named
Akhmetsadykova, Shynar, Baubekova, Almagul, Faye, Bernard, Kalimbetova, A., Konuspayeva, Gaukhar, Sandugash,   +5 more
core  

Relevance of lactate level detection in migrane and fibromyalgia [PDF]

, 2019
The aim of this study was to determine the blood lactate levels in healthy and pathological subjects, particularly with migraine and fibromyalgia. Moreover we investigated the possible correlation between lactate concentration, postural stability and ...
Amato, A, Brighina F, Brusa, J, Contrò, V, LO MONACO, Alessandra, Messina G, Proia, P   +6 more
core   +2 more sources

Dysoxia and lactate [PDF]

Archives of Disease in Childhood, 1999
Disturbances of oxygen supply or cellular oxygen metabolism are common in critically ill patients. An understanding of dysoxia, or oxygen limited energy depletion, requires an understanding of the normal physiology of cell oxygen metabolism, and the compensatory mechanisms that supply high energy molecules under conditions of hypoxia.
openaire   +3 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Investigation of nanofiltration as a purification step for lactic acid production processes based on conventional and bipolar electrodialysis operations [PDF]

, 2006
Nanofiltration was investigated for usability in a specific lactic acid production process based on conventional and bipolar electrodialysis operations.
Bouchoux, Antoine, Lutin, Florence, Roux-de Balmann, Hélène   +2 more
core   +2 more sources

Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

Nature Communications, 2020
Neutrophils provide first line of host defense against bacterial infections utilizing glycolysis for their effector functions. How glycolysis and its major byproduct lactate are triggered in bone marrow (BM) neutrophils and their contribution to ...
Eman Khatib-Massalha, Suditi Bhattacharya, H. Massalha, Adi Biram, Karin Golan, O. Kollet, Anju Kumari, F. Avemaria, Ekaterina Petrovich-Kopitman, S. Gur-Cohen, T. Itkin, Isabell Brandenburger, Asaf Spiegel, Ziv Shulman, Zachary Gerhart-Hines, S. Itzkovitz, M. Gunzer, S. Offermanns, R. Alon, A. Ariel, T. Lapidot   +20 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Production processes of fermented organic acids targeted around membrane operations: design of the concentration step by conventional electrodialysis [PDF]

, 2001
Organic acids are increasingly used for various industrial applications. Their production is mainly achieved by fermentation. Precipitation or extraction stages, which generate big amount of effluents, are then traditionally used to get the acid in a ...
Aimar, Pierre, Bailly, Mathieu, Cheryan, Munir, Lutin, Florence, Roux-de Balmann, Hélène   +4 more
core   +2 more sources

Prognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
BackgroundSepsis is a common critical condition caused by the body’s overwhelming response to certain infective agents. Many biomarkers, including the serum lactate level, have been used for sepsis diagnosis and guiding treatment.
Zhiqiang Liu, Zibo Meng, Yong-feng Li, Jingyuan Zhao, Shihong Wu, S. Gou, Heshui Wu   +6 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source