Results 181 to 190 of about 774,319 (342)

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Lactate: elucidating its indispensable role in human health. [PDF]

Mol Cancer
Zhang S, Wang J, Xu Z, Cheng Z, Shao B, Yu J.   +5 more
europepmc   +1 more source

A lactate metabolism-related gene signature to diagnose osteoarthritis based on machine learning combined with experimental validation

Jianhua Yang, Wenjun Li, Xuemei Lin, Liang Wei   +3 more
openalex   +1 more source

The Relationship between Serum Insulin-like Growth Factor-I and Changes in Body Weight in Early-Lactating Cows.

, 1999
Kazuhiko Nishimura, Satoru Shimizu, Hirofumi URATA, Yuzuru AOYAMA, Toyoji KOJIMA, Masando MATTA, Yoshikazu KAWABATA, Makiko Uchiyama, Keiichi SAKURAGI, Yoshihiro Ohnishi   +9 more
openalex   +2 more sources

2-Methoxyestradiol Reverses the Pro-Carcinogenic Effect of L-Lactate in Osteosarcoma 143B Cells [PDF]

, 2017
Magdalena Górska‐Ponikowska, Alicja Kuban‐Jankowska, Agnieszka Daca, Stephan Nußberger   +3 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Lactation.

Bulletin of the World Health Organization, 2010
Lactation is the most energy-efficient way to provide for the dietary needs of young mammals, their mother's milk being actively protective, immunomodulatory, and ideal for their needs. Intrauterine mammary gland development in the human female is already apparent by the end of the sixth week of gestation.
openaire   +1 more source

Effects of Transfusion on Serum Iron, Serum Lactate Dehydrogenase, and Platelets In Megaloblastic Anemia

, 1977
Georges Fillet, Jean-Marie Andrien, J Bury   +2 more
openalex   +2 more sources

Lactate Parameters Predict Clinical Outcomes in Patients with Nonvariceal Upper Gastrointestinal Bleeding [PDF]

, 2017
Seung Hoon Lee, Yang Won Min, Joohwan Bae, Hyuk Lee, Byung‐Hoon Min, Jun Haeng Lee, Poong‐Lyul Rhee, Jae J. Kim   +7 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source