Results 251 to 260 of about 505,953 (316)

A miniaturized implantable electrochemical platform for continuous monitoring of metabolites in deep tissue. [PDF]

Sci Adv
Madsen KE, Hintermueller D, Opel EA, Ribaudo JG, Saffari S, Cho S, Ciatti JL, Huang YT, Westman AM, Nuzzo RG, Pet MA, Rogers JA.   +11 more
europepmc   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Hepatocyte estrogen-related receptor α modulates a gluconeogenic-epigenetic crosstalk counteracting MASLD/MASH progression. [PDF]

Exp Mol Med
Gao J, Yang M, Duan R, Huang T, Li P, Gao L, Lu Z, Wong CW, Geng CA, Guan M.   +9 more
europepmc   +1 more source

Lactate in cardiogenic shock: pathophysiology, prognostic value, and clinical interpretation. [PDF]

Ann Intensive Care
Levy B, Hernandez G, Merdji H.
europepmc   +1 more source

Transcending metabolic acidosis: lactate as an epigenetic signal reprogramming diabetes-sepsis immunity. [PDF]

Front Immunol
Cai X, Han L, Liang Q.
europepmc   +1 more source

Lactate signaling and immune suppression in tumors: mechanisms and therapeutic implications. [PDF]

Cell Oncol (Dordr)
Wang X, Xiong D, Cui S, Duan B, Ding G, Huang Y, Wang Q.   +6 more
europepmc   +1 more source

Lactate Dehydrogenase B Expression in Cerebellum of Adult <i>Ube3a</i> ^m-/p+ Mice. [PDF]

MicroPubl Biol
Ramos Rivera MA, Torres Ortiz C.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Lactation in Anesthesiology

Anesthesiology Clinics, 2022
There are several work-related barriers to breastfeeding among physician mothers including: lack of appropriate place for breastmilk expression, unpredictable and inflexible schedules, and lack of time to breastfeed or express milk. In a survey of physician mothers, those who were in surgical and procedural subspecialties, including anesthesiology ...
Annery G, Garcia-Marcinkiewicz, Sarah S, Titler   +1 more
openaire   +2 more sources

CSF lactate

Practical Neurology, 2020
Lactate is produced from anaerobic glycolysis, which occurs in most tissues in the human body. Blood lactate is tested in most physiologically unwell patients in the Emergency Department and helps to guide treatment and prognosis. Cerebrospinal fluid (CSF) lactate, however, is not often measured.
Aravindhan Baheerathan, Robert DS Pitceathly, Carmel Curtis, Nicholas WS Davies   +3 more
openaire   +2 more sources