Results 301 to 310 of about 708,087 (381)

Studies on Lactate Dehydrogenase Isoenzymes in Human Gingiva

, 1966
Hisashi Takiguchi, Masayuki NATSUME, Eisuke FURUYAMA   +2 more
openalex   +2 more sources

Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial

Advanced Science, EarlyView.
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin, Sophie E. Davies, Martin Hewison, Kerry S. Jones, Javier T. Gonzalez, James A. Betts, Carl Jenkinson, Mark A. Lindsay, Sarah R. Meadows, Damon A. Parkington, Albert Koulman, Dylan Thompson   +11 more
wiley   +1 more source

Threshold estimation in running using dynamical correlations of RR intervals. [PDF]

Physiol Rep
Kanniainen M, Laatikainen-Raussi V, Pukkila T, Vohlakari K, Hynynen E, Ihalainen JK, Räsänen E.   +6 more
europepmc   +1 more source

Rapid and Noninvasive Early Detection of Lung Cancer by Integration of Machine Learning and Salivary Metabolic Fingerprints Using MS LOC Platform: A Large‐Scale Multicenter Study

Advanced Science, EarlyView.
Salivary metabolic signatures associated with lung cancer are systematically characterized through a self‐developed high‐throughput mass spectrometry Lab‐on‐a‐Chip platform. Utilizing these metabolic fingerprints, SalivaMLD, an integrated machine‐learning‐driven classification model is developed and demonstrates superior performance in detecting lung ...
Shuang Lin, Runlan Yan, Junqi Zhu, Bei Li, Yinyan Zhong, Shuang Han, Huiting Wang, Jianmin Wu, Zhao Chen, Yuyue Jiang, Aiwu Pan, Xuqing Huang, Xiaoming Chen, Pingya Zhu, Sheng Cao, Wenhua Liang, Peng Ye, Yue Gao   +17 more
wiley   +1 more source

Prognostic and therapeutic insights from lactate metabolism and tumor immune microenvironment in head and neck squamous cell carcinoma. [PDF]

Discov Oncol
Jiang H, Zhou L, Zhang H, Gong S, Yu Z.
europepmc   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

The association of umbilical hyperlactatemia with short- and tong-term outcomes in extremely low birth weight neonates: a matched cohort study. [PDF]

Eur J Pediatr
Hirsch L, Waitz M, Jenke A.
europepmc   +1 more source

A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions

Advanced Science, EarlyView.
An open‐source, low‐cost 3D perfusion system integrating bioprinted scaffolds and live‐imaging overcomes 2D culture limitations. Modeling the cerebrospinal fluid‐filled subarachnoid space, it reveals flow‐dependent focal adhesion kinase activation in meningothelial cells, demonstrating a powerful platform for studying mechanobiology and creating ...
Subashree Srinivasan, Valerie H. Huhle, Claudia C. Bippes, Nina Tanner, Stephan Frank, Hanspeter E. Killer, Corina Kohler, Albert Neutzner   +7 more
wiley   +1 more source

Tumor Microenvironment Lactate: Is It a Cancer Progression Marker, Immunosuppressant, and Therapeutic Target? [PDF]

Molecules
Kim EY, Abides J, Keller CR, Martinez SR, Li W.   +4 more
europepmc   +1 more source

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu, Aidan E. Gilchrist, Patrik K. Johansson, Yuan Guan, Jaydon D. Deras, Yu‐Chung Liu, Sofia Ceva, Michelle S. Huang, Renato S. Navarro, Annika Enejder, Gary Peltz, Sarah C. Heilshorn   +11 more
wiley   +1 more source