Results 311 to 320 of about 985,828 (404)
Lactate and lactylation: novel perspectives on fibrosis pathogenesis and therapeutic directions. [PDF]
Liang H, Xu L, Yang Y.
europepmc +1 more source
Metabolism of Pyruvate and L-Lactate by Rat Adipose Tissue
Karl Schmidt, Joseph Katz
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A structurally and functionally dual bionic bone adhesive is engineered through an organic–inorganic cohesion strategy, which significantly reinforces the adhesive's bone tissue adhesion as well as osteogenic activity. In a pioneering rabbit radius comminuted fracture model, the bone adhesive exhibits exceptional capability in immobilizing bone ...
Junyao Cheng+13 more
wiley +1 more source
Unraveling the causal nexus between serum lactate levels and cancer risk: A Mendelian randomization study. [PDF]
Yang L, Zheng Y, Li F, Yu J.
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NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu+14 more
wiley +1 more source
Effects of lactate concentration on T-cell phenotype and mitochondrial respiration. [PDF]
Cho E, Spielmann G, Irving BA.
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Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua+15 more
wiley +1 more source
The Role of Lactylation in Virus-Host Interactions. [PDF]
Zhao G, Zhou J, He S, Fei X, Guo G.
europepmc +1 more source