Results 321 to 330 of about 708,087 (381)

AARS2-catalyzed lactylation induces follicle development and premature ovarian insufficiency. [PDF]

Cell Death Discov
Zhang ZL, Ren ST, Yang WJ, Xu XW, Zhao SM, Fang KF, Lin Y, Yuan YY, Zhang XJ, Chen YQ, Xu W.   +10 more
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Research trends on lactate in cancer: a bibliometric analysis and comprehensive review (2015-2024). [PDF]

Front Immunol
Li S, Yang Z, Lv M, Zong L, Xie Y, Cai Z, Zhang Y, Wang Z, Liu Z, Sang L.   +9 more
europepmc   +1 more source

Hyperpolarized ¹³C-MRS can Quantify Lactate Production and Oxidative PDH Flux in Murine Skeletal Muscle During Exercise. [PDF]

NMR Biomed
Curtis MK, McGing JJ, Stubbs BJ, Ball V, Cochlin LE, O'Neill DP, Laustsen C, Cole MA, Robbins PA, Tyler DJ, Miller JJ.   +10 more
europepmc   +1 more source

Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes. [PDF]

Brain Behav
Bu Z, Zhou Y, Xu F, Xu S.
europepmc   +1 more source

Exogenous lactate infusion (ELI) in traumatic brain injury: higher dose is better? [PDF]

Crit Care
Vespa P, Wolahan S, Buitrago-Blanco M, Real C, Ruiz-Tejeda J, McArthur DL, Chiang JN, Agoston D, Glenn TC.   +8 more
europepmc   +1 more source

Identifying Risk Factors for Myocardial Injury in Elderly Patients with Sepsis. [PDF]

Med Sci Monit
Han YY, Yang JL, Meng HM, Wang P.
europepmc   +1 more source