Results 101 to 110 of about 231,763 (293)

Metabolic engineering of Lactococcus lactis: influence of the overproduction of alpha-acetolactate synthase in strains deficient in lactate dehydrogenase as a function of culture conditions

, 1995
Christ Platteeuw, Jeroen Hugenholtz, Marjo Starrenburg, I van Alen-Boerrigter, Willem M. de Vos   +4 more
openalex   +2 more sources

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

Lactate Dehydrogenase

Journal of Biological Chemistry, 1970
Pauline C. Yang, George W. Schwert
openaire   +2 more sources

Effects of Transfusion on Serum Iron, Serum Lactate Dehydrogenase, and Platelets In Megaloblastic Anemia

, 1977
Georges Fillet, Jean-Marie Andrien, J Bury   +2 more
openalex   +2 more sources

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Synthesis, characterization and Molecular docking simulation of novel Atorvastatin Aspirin ester, and study activation effect on lactate dehydrogenase enzyme in atherosclerosis patient

Tikrit Journal of Pure Science
This study involved synthesis of Atorvastatin Aspirin ester prodrug by reacting of aspirin drug with thionyl chloride SOCl2 to produce aspirinyl chloride that mixed with Atorvastatin drug which dissolved with acetone to produce corresponding ester.
Asmaa Ghazi Shukr Al-ajeely, Fadhil Dawood Khalid, Firas Taher Maher   +2 more
doaj   +1 more source

Use of inline measures of l-lactate dehydrogenase for classification of posttreatment mammary Staphylococcus aureus infection status in dairy cows [PDF]

, 2016
Carina Hildebrandt Jørgensen, Anders Ringgaard Kristensen, Søren Østergaard, Torben Werner Bennedsgaard   +3 more
openalex   +1 more source

Effect of serum lactate dehydrogenase-to-albumin ratio (LAR) on the short-term outcomes and long-term prognosis of colorectal cancer after radical surgery [PDF]

, 2023
Xin‐Peng Shu, Ying-Chun Xiang, Fei Liu, Yong Cheng, Wei Zhang, Dong Peng   +5 more
openalex   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source