Results 121 to 130 of about 344,963 (356)
CHANGES IN THE ISOZYME PATTERNS OF LACTATE DEHYDROGENASE (LDH) IN THE IN VITRO CULTURED MUSCLE CELLS [PDF]
Hajime Fujisawa
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Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
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Lactate dehydrogenase (LDH) activity in retinoblastoma
LDH estimation in aqueous and serum was carried out in 10 cases of retinoblastoma and 10 control cases (normal). LDH estimation was done by calorimetric method devised by King-Wooten (1964) (1).
Maurya OPS, Singh R, Rohatgi A, Shukla P
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Mitochondrial disorders in neuromuscular pathology
Introduction. With the advent of new drugs — analogues of mitochondrial metabolites, the widespread introduction into practice of research methods for assessing the function of mitochondria in patients with neurological pathology and other diseases ...
S. V. Kotov+2 more
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The kinetics of the reversible inhibition of heart lactate dehydrogenase through the formation of the enzyme–oxidized nicotinamide–adenine dinucleotide–pyruvate compound [PDF]
H. Gutfreund+4 more
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Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou+8 more
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THE ROLES OF SYNTHESIS AND DEGRADATION IN DETERMINING TISSUE CONCENTRATIONS OF LACTATE DEHYDROGENASE-5 [PDF]
Paul J. Fritz+3 more
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OVIDUCAL LACTATE DEHYDROGENASE [PDF]
Carla Gibson, Colin Masters
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This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang+8 more
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Introduction: Periodontitis is a chronic multi-factorial infectious disease characterized by irreversible destruction of collagen fibers and other matrix constituents of the gingival tissues and periodontal ligament, and resorption of alveolar bone ...
Arash Azizi+3 more
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