Results 201 to 210 of about 344,963 (356)

Bipyridine-Induced Synthesis of Lactate Dehydrogenase and Aldolase. [PDF]

, 1968
Germund Johansson, I. Elvebredd, J. Brunvoll, Gretchen Hagen, Jaakko Paasiv́irta   +4 more
openalex   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

The prognostic value of lactate dehydrogenase/albumin ratio in extranodal natural killer/T cell lymphoma. [PDF]

BMC Cancer
Li N, Feng Y, Chen X, Zou LQ.
europepmc   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Nuclear Lactate Dehydrogenase A Resists Cardiomyocyte Cell Cycle Arrest Induced by Oxidative Stress. [PDF]

J Cardiovasc Dev Dis
Cao M, Luo J, Fu K, Xu Y, Wang Y, Duan J, Chen R, Yuan W.   +7 more
europepmc   +1 more source

WTAP Mediated m6A Modification Stabilizes PDIA3P1 and Promotes Tumor Progression Driven by Histone Lactylation in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang, Qi You, Jiawei Liu, Xuguang Shen, Dengjun Huang, Xinlu Tao, Zhijie He, Chengwei Wu, Xinran Xi, Shouqiang Yu, Feng Liu, Zhihao Wu, Wenjun Mao, Shaojin Zhu   +13 more
wiley   +1 more source

MicroRNA 195, lactate dehydrogenase 5, phosphatase and tensin homologue in colorectal cancer: Clinicopathology and prognosis. [PDF]

World J Gastrointest Surg
Tang Z, Wen LM.
europepmc   +1 more source

Determination and Diagnostic Significance of Lactate Dehydrogenase Isoenzymes. H. A. Zondag. Van Gorcum & Company, Assen, The Netherlands, 1967, 118 pp., 16 gulden [PDF]

, 1968
Robert L. Dryer
openalex   +1 more source

Lactate dehydrogenase isoenzyme utilization [PDF]

Clinical Chemistry, 1996
Detlef Ritter, David S. Brink, P D Kelley, J H Joist   +3 more
openaire   +3 more sources

Exosomal CCT6A Secreted by Cancer‐Associated Fibroblasts Interacts with β‐Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric Cancer

Advanced Science, EarlyView.
Here, it is revealed that CAF‐secreted exosomal CCT6A enhances stemness, chemoresistance, and glycolysis in GC via the β‐catenin/c‐Myc/DDIT4‐TXNIP axis. Furthermore, CCT6P1, a pseudogene of CCT6A, is identified as upregulating CCT6A by competitively binding miR‐922, while c‐Myc transcriptionally activates both CCT6P1 and CCT6A.
Hui Sun, Tianqi Zhang, Xiaoyan Zhang, Yingxue Liu, Xu Wang, Xin Wang, Cong Tan, Shujuan Ni, Weiwei Weng, Meng Zhang, Lei Wang, Dan Huang, Xiaoyu Wang, Wenfeng Wang, Weiqi Sheng, Mi‐die Xu   +15 more
wiley   +1 more source