Results 71 to 80 of about 471,023 (292)

Serum Levels of Lactate Dehydrogenase and Alkaline Phosphatase Enzymes in Colorectal Cancer

, 2019
Colorectal cancer (CRC) remains one of the main public health problems throughout the world. It has recently been observed that both of lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) enzymes play critical role in cancer expansion.
Mohammed Imran Hamzah, Abeer Khalid Yaseen, Batool Hassan Al-Ghurabi   +2 more
core   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806

, 1995
The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate.
Moezelaar, R., Stal, L.J., de Teixeira, M.J.   +2 more
core   +2 more sources

Therapeutic Effect of Curcumin Oral Gel on Salivary Epidermal Growth Factor and Lactate Dehydrogenase Levels in Relation to Oral Mucositis in Head and Neck Cancer Patients Undergoing Concurrent Chemoradiation

Diyala Journal of Medicine
Background: Curcumin is a traditional herbal medication, which has shown promise in a variety of pharmacologic applications. Epidermal growth factor an amino acid polypeptide found in saliva and other bodily fluids, which promotes cell proliferation and
Rouaa S. Farhan, Fawaz D. Al-Aswad
doaj   +1 more source

Lactate dehydrogenase supports lactate oxidation in mitochondria isolated from different mouse tissues

Redox Biology, 2020
Research over the past seventy years has established that mitochondrial-l-lactate dehydrogenase (m-L-LDH) is vital for mitochondrial bioenergetics. However, in recent report, Fulghum et al.
Adrian Young, Catherine Oldford, Ryan J. Mailloux   +2 more
doaj   +1 more source

Pyruvate dehydrogenase : its structure, function and interactions within the pyruvate dehydrogenase multienzyme complex [PDF]

, 2002
Pyruvate dehydrogenase multi-enzyme complex (PDHC) is member of a family of multienzyme complexes that catalyse the irreversible decarboxylation of various 2-oxoacid substrates to their corresponding acyl-CoA derivatives, NADH and C02.
Hengeveld, A.F.
core  

Immunoglobulin A (lambda chains) conjugated with lactate dehydrogenase in serum.

, 1987
An atypical pattern for lactate dehydrogenase (EC 1.1.1.27) isoenzymes in a patient with sclerosis of the bladder neck was ascribable to complexing between lactate dehydrogenase and IgA.
Secchiero S, PLEBANI, MARIO, Burlina A, ZANINOTTO, MARTINA, Bertorelle R   +4 more
core   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Usefullness of Lactate Dehydrogenase and Lactate Dehydrogenase Isoenzymes for Diagnosis of Acute Myocardial Infarction

Survey of Anesthesiology, 1988
The usefulness of lactate dehydrogenase (LD) and LD isoenzymes in the diagnosis of acute myocardial infarction (AMI) is controversial. The present study reviewed 507 consecutive patients in whom creatine kinase, creatine kinase isoenzymes, LD and LD isoenzymes were ordered over a 1-month period. Of these, 249 had an insufficient number of serial enzyme
G J, Reis, H W, Kaufman, G L, Horowitz, R C, Pasternak   +3 more
openaire   +2 more sources