Results 61 to 70 of about 471,023 (292)
Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel +8 morewiley +1 more sourceGenome-Wide Association Study Identifies Two Novel Regions at 11p15.5-p13 and 1p31 with Major Impact on Acute-Phase Serum Amyloid A [PDF]
, 2010 Elevated levels of acute-phase serum amyloid A (A-SAA) cause amyloidosis and are a risk factor for atherosclerosis and its clinical complications, type 2 diabetes, as well as various malignancies.Illig, T, Spector Tim D., Kleber, M.E., März Winfried, Wichmann, H. -Erich, Mangino, M, Waldenberger, M, Hammond Christopher J., Prokopenko, I, Hammond, Christopher J., Blackburn Hannah, Prokisch Holger, Winkelmann Bernhard R., Mangino, M., H.-Erich Wichmann, Kovacs, P., Wichmann, H.-E., Marzi, C, Illig, T., Waldenberger, Melanie, Tim D Spector, Geistlinger, Ludwig, Tönjes, A, Koenig Wolfgang, Peters, Annette, Thorand, Barbara, Illig Thomas, Boehm, Bernhard O., Toenjes, Anke, Peters Annette, Boehm Bernhard O., Hysi, P.G., Kovacs, Peter, Prokisch, H., Mangino Massimo, Marcus E Kleber, Annette Peters, Prokopenko, I., Pirro G. Hysi, Soranzo, Nicole, Christopher J. Hammond, Hysi, Pirro G., Koenig, W, Tönjes Anke, Hammond, C.J., Heim, K., Harald Grallert, H-Erich Wichmann, Bernhard O. Boehm, Marzi, C., Koenig, W., Gieger, Christian, Eva Albrecht, Soranzo, N, Hammond, CJ, Albrecht Eva, Hysi Pirro G., Vasiliki Lagou, Grallert, H., Koenig, Wolfgang, Nicole Soranzo, Spector, Tim D., Gieger, C, Marz, W., Melanie Waldenberger, Michael Stumvoll, Thorand Barbara, Hysi, PG, Boehm, BO, Carola Marzi, Boehm, B.O., Janina S Ried, Lagou, Vasiliki, Wichmann, Heinz-Erich, Bernhard R. Winkelmann, Inga Prokopenko, Hannah Blackburn, Heim, Katharina, Kleber, ME, Peters, A, Stumvoll, M, Anke Tönjes, März, W, Gieger, C., Ried, Janina S., Christian Gieger, Ried, JS, Bernhard O Boehm, Albrecht, E, Blackburn, H, Stumvoll, M., Pirro G Hysi, Lagou Vasiliki, Ried Janina S., Waldenberger Melanie, Thorand, B, Christopher J Hammond, Lagou, V, Gieger Christian, Blackburn, Hannah, Grallert, Harald, Heim, K, Kleber Marcus E., Prokopenko Inga, Spector, T.D., Marzi, Carola, Waldenberger, M., Winkelmann, B.R., Heim Katharina, Wichmann H.-Erich, Kleber, Marcus E., Wolfgang Koenig, Barbara Thorand, Tönjes, A., Soranzo, N., Winfried März, Prokisch, Holger, Stumvoll, Michael, Marcus E. Kleber, Tim D. Spector, Mangino, Massimo, Stumvoll Michael, Grallert, H, Wichmann, HE, Geistlinger, L, Peters, A., Illig, Thomas, Maerz, Winfried, Ried, J.S., Grallert Harald, Thomas Illig, Albrecht, Eva, Lagou, V., Bernhard R Winkelmann, Kovacs Peter, Geistlinger Ludwig, Kovacs, P, Prokisch, H, Prokopenko, Inga, Katharina Heim, Marzi Carola, Soranzo Nicole, Massimo Mangino, Ludwig Geistlinger, Geistlinger, L., Blackburn, H., Peter Kovacs, Spector, TD, Janina S. Ried, Albrecht, E., Thorand, B., Winkelmann, BR, Winkelmann, Bernhard R., Holger Prokisch, Marzi, C;Albrecht, E;Hysi, PG;Lagou, V;Waldenberger, M;Tönjes, A;Prokopenko, I;Heim, K;Blackburn, H;Ried, JS;Kleber, ME;Mangino, M;Thorand, B;Peters, A;Hammond, CJ;Grallert, H;Boehm, BO;Kovacs, P;Geistlinger, L;Prokisch, H;Winkelmann, BR;Spector, TD;Wichmann, HE;Stumvoll, M;Soranzo, N;März, W;Koenig, W;Illig, T;Gieger, C +154 morecore +2 more sourcesLignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase
Advanced Materials, EarlyView.Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT
FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He +14 morewiley +1 more sourcePattern of hemolysis parameters and association with fetal hemoglobin in sickle cell anemia patients in steady state
Revista Brasileira de Hematologia e Hemoterapia, 2015 Objective: This study aimed to evaluate the influence of fetal hemoglobin (Hb F) on hemolysis biomarkers in sickle cell anemia patients. Methods: Fifty adult sickle cell anemia patients were included in the study.Juliane Almeida Moreira, Marília Rocha Laurentino, Rosângela Pinheiro Gonçalves Machado, Maritza Cavalcante Barbosa, Ronaldo Pinheiro Gonçalves, Amanda de Menezes Mota, Lilianne Brito da Silva Rocha, Alice Maria Costa Martins, Alcínia Braga de Lima Arruda, Iêda Pereira de Souza, Romélia Pinheiro Gonçalves +10 moredoaj +1 more sourceBio-Mimicking Pyruvate to Inhibit Lactate Dehydrogenase [PDF]
, 2012 Lactate dehydrogenase is an enzyme that catalyzes the reaction of converting pyruvic acid into lactic acid. This reaction took place at pH 7.0. Molecules, such as acetamide and oxamic acid, which are believed to mimic pyruvate in terms of hydrogen ...Brockington, Davita Nicole, NC DOCKS at The University of North Carolina at Pembroke +1 morecore A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance
Advanced Science, EarlyView.This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler +17 morewiley +1 more sourceCystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration
Haematologica, 2009 Background Renal impairment is a common complication of multiple myeloma. Cystatin-C is considered an accurate marker of glomerular filtration rate in several renal disorders.Evangelos Terpos, Eirini Katodritou, Evangelos Tsiftsakis, Efstathios Kastritis, Dimitrios Christoulas, Anastasia Pouli, Eurydiki Michalis, Evgenia Verrou, Konstantinos Anargyrou, Konstantinos Tsionos, Meletios A. Dimopoulos, Konstantinos Zervas +11 moredoaj +1 more source
