Results 271 to 280 of about 77,943 (339)

Can a mechanical circulatory support comprehensive approach to cardiogenic shock at referral centers reduce 30-day mortality? [PDF]

Front Cardiovasc Med
Pieri M, Iannaccone M, Burzotta F, Botti G, Aurigemma C, Trani C, Ajello S, Altizio S, Sanna T, Romagnoli E, Paraggio L, Cappannoli L, Scandroglio AM, Chieffo A.   +13 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Uterine Transplant Optimization From a Preclinical Donor Model With Controlled Cardiocirculatory Arrest. [PDF]

Transplant Direct
Loiseau E, Mesnard B, Bruneau S, De Sousa C, Bernardet S, Hervouet J, Minault D, Levy S, Le Gal A, Dion L, Blancho G, Lavoue V, Branchereau J.   +12 more
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Pre-admission beta-blocker therapy and outcomes in cardiogenic shock: Insights from the Altshock-2 Registry. [PDF]

ESC Heart Fail
Pagnesi M, Riccardi M, Sacco A, Tavecchia G, Viola G, Frea S, Briani M, Bertoldi LF, Bertaina M, Potena L, Valente S, Marini M, De Ferrari GM, D'Ettore N, Cardinale A, Camporotondo R, Rota M, Tavazzi G, Morici N, Pappalardo F, Metra M, Altshock‐2 investigators.   +21 more
europepmc   +1 more source

Hydrodeoxygenation of Bio‐polymer Precursors with Base Metal Catalysts [PDF]

, 2017
Khokarale, Santosh Govind, Riisager, Anders, Shunmugavel, Saravanamurugan   +2 more
core  

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

Venoarterial Partial Pressure of Carbon Dioxide Difference: Let's Trend It! [PDF]

Indian J Crit Care Med
Ravisankar NP.
europepmc   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Effects of Dexamethasone on Cognitive Functions After Coronary Artery Bypass Grafting Surgery. [PDF]

Medicina (Kaunas)
Umbrasas T, Švagždienė M, Andrejaitienė J, Kasputytė G.   +3 more
europepmc   +1 more source