Results 291 to 300 of about 320,077 (372)

Chimeric Nanozyme Bacterial Outer Membrane Vesicles Reprograming Tumor Microenvironment for Safe and Efficient Anticancer Therapy

Advanced Science, EarlyView.
This study reports an innovative strategy to improve the safety of OMVs by shielding them with a sophisticated shell composed of DaFe shell and Au nanoparticles, which not only reduces the toxicity of OMVs during circulation but also enables rapid release of these therapeutically active components in tumor for combined therapy involving glucose ...
Fan Zhang, Qianqian Li, Haibing Dai, Weiqun Li, Xiang Chen, Huibin Wu, Shanming Lu, Ran Luo, Feng Li, Guihong Lu, Jianbo Yu, Lin Mei   +11 more
wiley   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Value of APACHE II, SOFA and CardShock scoring as predictive tools for cardiogenic shock: A single-centre pilot study. [PDF]

ESC Heart Fail
Chlabicz M, Łaguna W, Kazimierczyk R, Kazimierczyk E, Łopatowska P, Gil M, Sobkowicz B, Kamiński KA, Tycińska A.   +8 more
europepmc   +1 more source

Postoperative Hyperbilirubinemia and Acute Liver Dysfunction after Cytoreductive Surgery and HIPEC. [PDF]

Indian J Crit Care Med
Kannancheeri A, Solanki SL, Kazi M, Saklani A.   +3 more
europepmc   +1 more source

Capillary Refill Time as a Part of Routine Physical Examination in Critically Ill Patients Undergoing Vasoactive Therapy: A Prospective Study. [PDF]

J Clin Med
Wesołek F, Putowski Z, Staniszewska W, Latacz R, Krzych ŁJ.   +4 more
europepmc   +1 more source

First use of the Impella 5.5 in a patient with cardiogenic shock to bridge to heart transplantation in Poland. [PDF]

Cardiol J
Przybylski R, Błaziak M, Bochenek M, Jarosz A, Barteczko-Grajek B, Zakliczyński M, Sokolski M, Garus M, Gajewski P, Iwanek G, Skalec T, Reczuch K, Kuliczkowski W.   +12 more
europepmc   +1 more source

Intravenous iron supplementation improves energy metabolism of exercising skeletal muscles without effect on either oxidative stress or inflammation in male patients with heart failure with reduced ejection fraction. [PDF]

Cardiol J
Drozd MD, Tkaczyszyn M, Kasztura M, Węgrzynowska-Teodorczyk K, Flinta I, Banasiak W, Ponikowski P, Jankowska EA.   +7 more
europepmc   +1 more source

Epidemiology, clinical and biological characteristics, and prognosis of critically ill COVID 19 patients: a single-center experience through 4 successive waves. [PDF]

Pneumonia (Nathan)
Tchakerian S, Besnard N, Brunot V, Moulaire V, Benchabane N, Platon L, Daubin D, Corne P, Machado S, Jung B, Bendiab E, Landreau L, Pelle C, Larcher R, Klouche K.   +14 more
europepmc   +1 more source

Urinary Lactate-To-Creatinine Ratio during the First Days of Life Correlates with the Degree of Brain Damage in Premature Infants.

Neonatology
Zasada M, Olszewska M, Kowalik A, Berska J, Bugajska J, Karcz P, Herman-Sucharska I, Kwinta P.   +7 more
europepmc   +1 more source