Results 251 to 260 of about 339,670 (343)

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Exploring the Influence of Parity on Metabolic Profile, Performance and Offspring Growth in <i>Bos indicus</i> Beef Cows. [PDF]

Vet Sci
Rodrigues II, Ferreira ML, Rennó LN, Marcos NA, da Silva Júnior RG, Siqueira IP, Magalhães CP, Detmann E, Valadares Filho SC.   +8 more
europepmc   +1 more source

Rank correlations and product moment correlations among different methods of breeding value estimation for first lactation milk yield and life time traits in Sahiwal cattle

, 2017
Jaswant Singh, CV Singh, BN Shahi
openalex   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

Advanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme, Rocio K. Finol‐Urdaneta, Jeffrey R. McArthur, Nicholas R. Marzano, Simon Maksour, Amarinder Thind, Yang Guo, Dominic Kaul, Marnie Maddock, Oliver Friedrich, Boris Martinac, David J. Adams, Mirella Dottori   +12 more
wiley   +1 more source

A Bio-Economic Evaluation of Var, LnVar, and r-Auto Resilience Indicators in Czech Holstein Cattle. [PDF]

Animals (Basel)
Krupová Z, Kašná E, Zavadilová L, Krupa E.   +3 more
europepmc   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

From BIA to BMI: A New Look at Postpartum Recovery and Breastfeeding Outcomes. [PDF]

Metabolites
Mazur D, Purc-Bandurko K, Kimber-Trojnar Ż, Trojnar M, Leszczyńska-Gorzelak B.   +4 more
europepmc   +1 more source

Evaluating Lactation Persistency, Lactation Curve Parameters, and Dairy Efficiency: The Role of Parity, Calving Season, and Days Open in Holstein-Friesian Cows [PDF]

Serdar Güler, Ali Akmaz
openalex   +1 more source

Antifouling All‐Polymeric Microneedle Array for Long‐Term Wearable ECG Monitoring

Advanced Science, EarlyView.
A biocompatible, all‐polymeric MNEs designed for long‐term ECG monitoring is developed. Coated with PEDOT:Tos and zwitterionic SBMA, the MNEs offer ultra‐low impedance and antifouling properties. After 14 days of continuous use, the MNEs accurately detected PQRST complexes, highlighting its potential for long‐term, real‐time ECG monitoring in everyday ...
Ju Hyeon Kim, Chuljin Hwang, Jee Hoon Lee, Hang Chan Jo, Dae Yu Kim   +4 more
wiley   +1 more source

Drug exposure during breastfeeding: a descriptive population-based cohort study with SIDIAP database. [PDF]

Int Breastfeed J
Giner-Soriano M, Ricart GA, Cartanyà-Hueso À, Gomez-Lumbreras A, Vázquez ML, Morros R, Vedia C.   +6 more
europepmc   +1 more source