Results 241 to 250 of about 829,404 (286)

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao   +8 more
wiley   +1 more source

Metabolic Trajectory and Metabolic Robustness Assessment of Grazing Dairy Cows Through an Integrative Approach. [PDF]

open access: yesJ Anim Physiol Anim Nutr (Berl)
Jorge-Smeding E   +8 more
europepmc   +1 more source

Volatile Organic Compound Metabolites Are Found in the Urine of Breastfed Infants Whose Mothers Use Cannabis: The Lactation and Cannabis (LAC) Study. [PDF]

open access: yesInt J Environ Res Public Health
Samartino S   +10 more
europepmc   +1 more source

Documented In-Hospital Lactation Support and Exclusive Breastfeeding During the Postpartum Stay.

open access: yesJAMA Netw Open
Gallagher TT   +7 more
europepmc   +1 more source

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