Results 281 to 290 of about 3,019,565 (364)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Polystyrene microplastics induce potential toxicity through the gut-mammary axis. [PDF]

NPJ Sci Food
Wang Z, Wang S, Liu S, Wang Z, Li F, Bu Q, An X.   +6 more
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Community-based doulas and medicaid expansion: a resource-based approach to support the well-being of low-income postpartum women. [PDF]

BMC Pregnancy Childbirth
Farewell CV, Gahrns J, Pangalangan J, Curl E, Pangalangan A.   +4 more
europepmc   +1 more source

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Safety and Risks of Antihypertensive Medications During Breastfeeding: A Review of Current Guidelines. [PDF]

J Clin Med
Piotrkowicz E, Skrzypczyk P, Prejbisz A, Dobrowolski P, Gawlak M, Kosiński P.   +5 more
europepmc   +1 more source

Gold‐Dithiocarbamato Glycoconjugates as Potential Anticancer Agents: Design, Physico‐Chemical Characterization and In Vitro Biological Activity

ChemBioChem, Accepted Article.
In order to develop new metal‐based glycoconjugates as potential anticancer agents, three gold(III)‐dithiocarbamato glycoconjugates of the type [AuIIIBr2(SSC‐Inp‐GlcN)] (Au3‐5), their gold(I)‐phosphine counterparts [AuI(SSC‐Inp‐GlcN)(PPh3)] (AuP3‐5) and gold(I)‐carbene analogues [AuI(SSC‐Inp‐GlcN)(Et2BzImy)] (AuC3‐5) (Inp: isonipecotic moiety; GlcN ...
Andrea Pettenuzzo, Jessica Wölker, Luciano Marchiò, Ingo Ott, Luca Ronconi   +4 more
wiley   +1 more source

Probiotic L. reuteri treatment in stressed rats improves maternal care and corrects corticosterone-BDNF-oxytocin balance offering insights for maternal postpartum distress treatment. [PDF]

Sci Rep
Benlakehal R, Gaetano A, Charlet R, Bouwalerh H, Cogez V, Harduin-Lepers A, Sendid B, Nicoletti F, Maccari S, Morley-Fletcher S.   +9 more
europepmc   +1 more source

Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Matteo Lucchelli, Davide Tommaso Andreis, Mattia Gomarasca, Giovanni Mistraletti   +3 more
wiley   +1 more source