Results 261 to 270 of about 44,362 (300)
Some of the next articles are maybe not open access.
Lactate: A New Target for Brain Disorders
NeuroscienceLactate in the brain is produced endogenously and exogenously. The primary functional cells that produce lactate in the brain are astrocytes. Astrocytes release lactate to act on neurons, thereby affecting neuronal function, through a process known as the astrocyte-neuron shuttle.
Shunfeng Liu, Shouhong Zhou
openaire +2 more sources
The Diagnostic Utility of Lactate Sensitivity in Panic Disorder
Archives of General Psychiatry, 1990Lactate infusion is the most extensively studied of the pharmacological challenge tests in panic disorder. We assessed the value of this test in the diagnosis and subtyping of panic in clinical and research settings. Analysis of lactate infusion studies to date suggests that patients with panic attacks are significantly more sensitive to lactate than ...
D S, Cowley, G W, Arana
openaire +2 more sources
Prescribing for psychiatric disorders in pregnancy and lactation
Best Practice & Research Clinical Obstetrics & Gynaecology, 2001The most recent Confidential Enquiry into the causes of maternal deaths during the perinatal period in England and Wales (1994–1996) revealed that psychological illness was at least as important as hypertensive disorders. It is therefore important for obstetricians to be aware of a variety of psychiatric conditions as well as the psychotropic ...
Craig, M, Abel, K
openaire +2 more sources
Hyperventilation and lactate metabolism in panic disorder
Biological Psychiatry, 1989392 elderly subjects (ages 60-79) were administered a battery of tests of memory and attention to assess the acute and chronic effects of placebo, 2.5 mg and 10 mg diazepam. The elderly showed increased sensitivity to the adverse acute effects of a single dose on some performance measures (not attributable to differences in plasma drug concentration ...
Richard Maddock, Cameron Carter
openaire +1 more source
Clinical Presentations of Breast Disorders in Pregnancy and Lactation
2020The breast tissue undergoes significant physiological change during pregnancy and lactation. These changes can give rise to some unique disorders during pregnancy , puerperium and lactation or exaggerate pre-existing conditions. Clinical examination becomes less reliable due to textural change and density of breast tissue as a result of hormonal ...
openaire +2 more sources
Panic disorder: Response to sodium lactate and treatment with antidepressants
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1985Effective drugs for mental disorders have been found by serendipitous findings not supported by knowledge of psychopharmacology. Drug are assigned labels, such as "antidepressant" without knowledge that such a label delimits the utility of such agents. Many double-blind controlled studies have shown that imipramine effectively ameliorates panic attacks
A, Rifkin, S G, Siris
openaire +2 more sources
Lactate sensitivity and cardiac cholinergic function in panic disorder
American Journal of Psychiatry, 1994Using spectral analysis of the continuous time series signal before and during lactate and placebo infusions, the authors studied heart rate variability in six patients with panic disorder and nine normal comparison subjects. The decrease in high-frequency (0.20-0.50 Hz) power and the increase in sympathovagal ratios (mid-frequency [0.07-0.15 Hz] to ...
V K, Yeragani +4 more
openaire +2 more sources
Effect of Flumazenil in Lactate-Sensitive Patients With Panic Disorder
American Journal of Psychiatry, 1998Flumazenil is a benzodiazepine receptor antagonist that has been reported to provoke panic attacks in patients with panic disorder. This study was undertaken to compare the effects of flumazenil and sodium lactate, the most widely studied panic provocation agent.Ten patients with panic disorder were given infusions of saline, sodium lactate, and ...
Ströhle, A. +4 more
openaire +3 more sources
Lactate overproduction in platelets of subjects affected with myeloproliferative disorders
Scandinavian Journal of Haematology, 1985In platelets of patients affected with myeloproliferative disorders, glycolytic and glycogenolytic flux have been examined. Results of studies on glucose uptake, glycogen breakdown and lactate formation have been reported. No difference in glucose uptake between controls and patients was observed, but in patients a higher lactate formation was always ...
G, Leoncini +3 more
openaire +2 more sources
Screening and treatment of anxiety disorders in pregnant and lactating women
Women's Health Issues, 2002Untreated anxiety disorders during pregnancy and the postpartum period may pose significant risks to the unborn fetus and interfere with a mother's ability to properly care for her newborn child. As the symptoms of anxiety disorders are often similar to those found in pregnancy, careful screening for anxiety disorders in pregnant women is essential ...
Risa B, Weisberg, Julie A, Paquette
openaire +2 more sources