Results 161 to 170 of about 2,179,464 (293)

Comparison of Milk Yield, Peak Yield and Lactation Length of Healthy and Mastitic Friesian Dairy Cows in Sudan

, 2006
This paper had been presented for promotion at the university of Khartoum. To get the full text please contact the other at Ibtisammohamed@hotmail.comThe present study confirmed a significant ...
ElYas, Ibtisam
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H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Lactation performance data for grey seals (Halichoerus grypus) from 1999-2004.

, 2011
Individually marked, free-ranging grey seal (Halichoerus grypus) females were sampled longitudinally over 6 breeding seasons (1999-2004) on Sable Island, Nova Scotia, Canada.

core  

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

Early-life milk production traits predict lifetime milk yield and support replacement decisions in Holstein, Jersey and Crossbred dairy cows under subtropical conditions. [PDF]

Vet Anim Sci
Tshona O, Mpetile Z, Akinmoladun OF.
europepmc   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

Leukocyte Profiles in Breeding Female and Pup Southern Elephant Seals (<i>Mirounga leonina</i>) in Relation to Lactation and Body Condition. [PDF]

Animals (Basel)
Descayrac P, Bichet C, Badaut J, Picard B, Guinet C, López-Ramon J, Lizana V, Gilbert C.   +7 more
europepmc   +1 more source

Effect of farming region and calving season on complete-lactation production traits in simmental cows

, 2019
The present research focused on analysing the effect of farming region, calving season and their interaction on complete-lactation milk performance traits (lactation length, milk production, milk fat production, and milk fat content) using the ...
Đoković, Radojica, Petrović, Miloš, Đedović, Radica, Bogosavljević-Bošković, Snežana, Rakonjac, Simeon, Petrović, Milun, Bogdanović, Vladan   +6 more
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