Results 201 to 210 of about 2,179,464 (293)

Effects of Mare Age and Number of Foalings on Body Morphometry, Udder Morphology, Milk Yield, and Milk Composition in Kushum Mares. [PDF]

open access: yesAnimals (Basel)
Toishimanov M   +13 more
europepmc   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

open access: yesAdvanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao   +10 more
wiley   +1 more source

Physiological, genetic and inflammatory factors influencing somatic cell count in goat milk: a review. [PDF]

open access: yesActa Vet Scand
Einorytė J   +4 more
europepmc   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Heat Stress, Indoor Microclimate, and Lactation Feed Intake in Commercial Mediterranean Sows: Parity Effects and a Daily Resolution Predictive Model. [PDF]

open access: yesLife (Basel)
Fotos L   +11 more
europepmc   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

open access: yesAdvanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao   +11 more
wiley   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen   +12 more
wiley   +1 more source

Growth Performance, Milk Productivity, Productive Longevity, and Milk Composition of Mugalzhar Horses. [PDF]

open access: yesAnimals (Basel)
Toishimanov M   +13 more
europepmc   +1 more source

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