Results 121 to 130 of about 101,713 (298)

Effects of stage and number of lactation on the chemical composition of goat milk

Czech journal of animal science, 2001
The aim of this research was to establish the effects of stage and number of lactation on changes in the chemical composition of goat milk (Alpine and Saanen) during five consecutive lactation periods. All animals were milked manually and kept under the same accomodation and feeding conditions.
Mioč, Boro, Pavić, Vesna, Samaržija, Dubravka, Antunac, Neven, Havranek, Jasmina   +4 more
openaire   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Working at the interface between the art and science of breastfeeding: a qualitative study of International Board Certified Lactation Consultants' experiences.

2 This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and due acknowledgment must always be made of the use of any material contained in, or derived from ...
Brown, Sarah Jane
core  

INFLUENCE OF STAGE AND NUMBER OF LACTATION ON SUCCESS OF THE ARTIFICIAL INSEMINATION IN DAIRY COWS

, 2014
The objective of this study was to analyse the influence of stage of lactation and parity(number of lactations) on success of the artificial insemination in Holstein-Fresian dairy cows.
Găvan, Constantin, Motorga, Vergil
core  

Relationship of stage and number of lactation with somatic cell count in milk of Paška sheep [PDF]

, 2019
S obzirom da se mlijeko paških ovaca prerađuje u istoimeni sir, važna je higijenska ispravnost proizvedenog mlijeka. Osim genetskih čimbenika, na proizvodnju i kvalitetu mlijeka utječe i velik broj okolišnih čimbenika, s obzirom na navedeno cilj ...
Počekal, Martina
core  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Milk Yield Prediction Using Animal and Production Features: Optimal Combinations and Machine Learning Approaches

Turkish Journal of Agriculture: Food Science and Technology
This study investigated the factors influencing milk yield in dairy cattle, the determination of optimal combinations, and the predictive performance of machine learning (ML) models.
Demet Çanga Boğa, Mustafa Boğa
doaj   +1 more source

Mammary cell number, proliferation, and apoptosis during a bovine lactation: relation to milk production and effect of bST

, 2001
This investigation evaluated mammary cell loss and replacement during lactation and the impact of administration of bST on these processes. During lactation, a gradual decrease in number of mammary epithelial cells within the mammary glands occurs and ...
Wood, DL, Paape, MaxDI01802000326604FA1B1996-F0ED-11E1-A9DE-61C894A0A6B4, Paape, Max, Mcleod, K, Capuco, AnthonyDI018020005793091C1B8F8A-F0EE-11E1-A9DE-61C894A0A6B4, Capuco, Anthony, Baldwin, R   +6 more
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source