Results 221 to 230 of about 194,001 (308)

The effect of litter size relative to functional teat count on lactating sow and litter performance. [PDF]

Transl Anim Sci
Jenkins AK, Collier SM, DeRouchey JM, Tokach MD, Woodworth JC, Gaffield KN, Gebhardt JT, Goodband RD, Coble KF, Corns PJ, Karl J, Bradley T.   +11 more
europepmc   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Maternal nutrition can rapidly rescue a nephron deficit in low birthweight offspring. [PDF]

NPJ Metab Health Dis
Cullen-McEwen LA, Gazzard SE, Gonçalves G, Rose AJ, Eliades J, de Zoysa N, Moreau JLM, Hayatudin R, Solon-Biet SM, Wu Y, Mathangasinghe Y, Simpson SJ, Combes AN, Bertram JF.   +13 more
europepmc   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Luminal hormone-responsive cells tune the regenerative remodeling of mammary glands in large mammals. [PDF]

Cell Discov
Li Y, Zhang L, Luo T, Zhang W, Wang T, Liu F, Lin S, Luo J, Liu J, Peng J, Wang C, Wang W, Shi H.   +12 more
europepmc   +1 more source

Special Report, No. 5 [PDF]

, 1956
Sweetman, William J.
core  

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Association of Metabolic Disease Occurrence on Milk Fatty Acid Composition and Rumination Time in Early Lactation Dairy Cows and Evaluation of Their Potential as Diagnostic Indicators. [PDF]

Anim Sci J
Nagahaka N, Abe E, Matamura M, Hiraoka H, Kondo M.   +4 more
europepmc   +1 more source

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen, Aleksandr Barulin, Won Jong Yu, Jong‐Chan Park, Inki Kim   +4 more
wiley   +1 more source

Genetic Evaluation of Milk Production Traits in the Serbian Saanen Goat Population. [PDF]

Animals (Basel)
Zeljić Stojiljković K, Mićić N, Bogdanović V, Đedović R, Pihler I, Stojiljković N, Stanojević D.   +6 more
europepmc   +1 more source