Results 241 to 250 of about 101,713 (298)

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

open access: yesAdvanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen   +11 more
wiley   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

open access: yesAdvanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang   +11 more
wiley   +1 more source

Lactation Interrupted: PFAS Impact on Capacity to Breastfeed Ignored. [PDF]

open access: yesCurr Environ Health Rep
Pelch KE   +4 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

Age Influences the Bacterial Composition of Samples From Buffaloes in the Marajó Archipelago, Pará, Brazilian Amazon. [PDF]

open access: yesEnviron Microbiol Rep
Lima ALA   +9 more
europepmc   +1 more source

The relationship of forage intake, residual feed intake, and greenhouse gas emissions between lactation and gestation in beef cows. [PDF]

open access: yesTransl Anim Sci
Talley SR   +8 more
europepmc   +1 more source

Genetic and non-genetic determinants of farrowing and lactation traits in multiparous sows under intensive management. [PDF]

open access: yesArch Anim Breed
González-Sánchez D   +7 more
europepmc   +1 more source

Maternal Cadmium Exposure Impairs Lactational Performance and Milk Quality in Mice. [PDF]

open access: yesBiology (Basel)
Kuang M   +6 more
europepmc   +1 more source

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