This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Phenotypic effects of calving ease on the subsequent fertility and milk production of dam and calf in UK Holstein-Friesian heifers [PDF]
The effect of calving ease on the fertility and production performance of both dam and calf was studied in approximately 50,000 and 10,000 UK Holstein-Friesian heifers and heifer calves, respectively. The first objective of this study was to estimate the
Alonso-Spilsbury +55 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The importance of hoof health in dairy production
The objective of this study was to evaluate the association of hoof health on reproduction and production performance, somatic cell count, and longevity in dairy cattle.
Lenka Krpálková +3 more
doaj +1 more source
The effect of measure number of milk production (MP) on the estimation of parameters in typical and extended lactations curve parameters of local goats was evaluated.
GLAFIRO TORRES-HERNÁNDEZ +6 more
doaj +1 more source
Organic dairy cows: milk yield and lactation characteristics in thirteen established herds and development of a herd simulation model for organic milk production [PDF]
As a consequence of organic standards and principles, organic dairy producers are frequently faced with a different set of management considerations than those found in conventional dairy systems.
Hovi, M
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Effects of Feeding Bt Maize to Sows during Gestation and Lactation on Maternal and Offspring Immunity and Fate of Transgenic Material [PDF]
peer-reviewedBackground: We aimed to determine the effect of feeding transgenic maize to sows during gestation and lactation on maternal and offspring immunity and to assess the fate of transgenic material.
Buzoianu, Stefan G. +10 more
core +6 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Comparative study of lactation curves and milk quality in Holstein versus Swedish Red and White-Holstein Cross Cows [PDF]
The objective of this study reported in this research paper was to compare the lactation curves of the production of milk, fat, protein, percentages of fat and protein, and somatic cell score in purebred Holstein (H) cows and Swedish Red and White (SRW) -
Lembeye, Felipe +4 more
core +1 more source

