Results 51 to 60 of about 194,001 (308)

Genetic parameters for milk mineral content and acidity predicted by mid-infrared spectroscopy in Holstein–Friesian cows [PDF]

, 2015
peer-reviewedThis article was first published in animal, Volume 9, Issue 05, May 2015, pp 775-780 © The Animal Consortium 2015The aim of the present study was to estimate genetic parameters for calcium (Ca), phosphorus (P) and titratable acidity (TA) in ...
Berry, Donagh, Cassandro, M., de Marchi, M., McParland, Sinead, Penasa, M., Toffanin, V.   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Effects of Electrical Conductivity, Activity Level, Age and Lactation Number on Milk Yield in Dairy Cows during the Lactation Period

Livestock Studies
This study aimed to evaluate the relationships between milk yield and variables such as milk electrical conductivity, animal activity, age, and lactation number. The study was based on 2022 data from Holstein cows on a private dairy farm located in the Karapınar district of Konya, Türkiye.
Tamer Kayar, Onur Erzurum
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Response to somatic cell count-based selection for mastitis resistance in a divergent selection experiment in sheep [PDF]

, 2009
A divergent selection experiment in sheep was implemented to study the consequences of log-transformed somatic cell score (SCS)-based selection on resistance to natural intramammary infections.
Aurel, Marie-Rose, Bergonier, Dominique, Dion, Stéphane, Foucras, Gilles, Hygonenq, Marie-Claude, Robert-Granié, Christèle, Rupp, Rachel   +6 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Milk Yield and Composition, Technological Properties and Homeostasis Indices at Different Lactation Stages and Parities of Two Polish Dairy Goat Breeds

Acta Universitatis Cibiniensis. Series E: Food Technology, 2023
The purpose of the research was to determine the effect of breed, lactation number, and lactation stage on milk efficiency and goat milk ingredients, these being indicators of milk technological parameters and homeostasis disturbances.
Urbańska Daria Maria, Puchała Ryszard, Jarczak Justyna, Barłowska Katarzyna, Czopowicz Michał, Mickiewicz Marcin, Kaba Jarosław, Bagnicka Emilia   +7 more
doaj   +1 more source

The effect of Holstein-Friesian genotype and feeding system on selected performance parameters of dairy cows on grass-based systems of milk production in Ireland [PDF]

, 2006
End of project reportThe overall objective of this project was to assess, the effect of strain of Holstein-Friesian dairy cow, pasture-based feed system (FS) and their interaction on animal performance in terms of milk productivity and lactation profile,
Berry, Donagh, Buckley, James F., Dillon, Pat, Horan, Brendan, Linnane, M., McCarthy, S., Mee, John F, O’Connor, Paula M., Shalloo, Laurence   +8 more
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source