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Nanoscale, 2020
Lactic acidosis is one of the key characteristics of the tumor microenvironment (TME), and plays a critical role in therapy resistance, making it an attractive target for enhancing anticancer treatment.
Xia Meng +9 more
semanticscholar +1 more source
Lactic acidosis is one of the key characteristics of the tumor microenvironment (TME), and plays a critical role in therapy resistance, making it an attractive target for enhancing anticancer treatment.
Xia Meng +9 more
semanticscholar +1 more source
MedicationāInduced Hyperlactatemia and Lactic Acidosis: A Systematic Review of the Literature
Pharmacotherapy, 2019Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medicationāinduced hyperlactatemia and lactic acidosis are diagnoses of exclusion and have the potential to be overlooked.
Zachary R. Smith +2 more
semanticscholar +1 more source
Intensive Care Medicine, 2003
The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients.
openaire +3 more sources
The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients.
openaire +3 more sources
Enzyme, 1987
For use in screening for disorders of pyruvate metabolism in cultured skin fibroblasts, we developed a sensitive assay method for measuring the rates of decarboxylation of (1-14C)-pyruvate using dichloroacetate (DCA). By this method, disorders of the mechanism of activation of pyruvate dehydrogenase (PDH) were found in 2 of 10 patients with congenital ...
Y, Kuroda +4 more
openaire +2 more sources
For use in screening for disorders of pyruvate metabolism in cultured skin fibroblasts, we developed a sensitive assay method for measuring the rates of decarboxylation of (1-14C)-pyruvate using dichloroacetate (DCA). By this method, disorders of the mechanism of activation of pyruvate dehydrogenase (PDH) were found in 2 of 10 patients with congenital ...
Y, Kuroda +4 more
openaire +2 more sources

